Enhanced desensitization followed by unusual resensitization in GABA^sub A^ receptors in phospholipase C-related catalytically inactive protein-1/2 double-knockout mice

Phospholipase C-related catalytically inactive proteins (PRIP-1/2) are previously reported to be involved in the membrane trafficking of GABA^sub A^ receptor (GABA^sub A^R) and the regulation of intracellular Ca^sup 2+^ stores. GABA^sub A^R-mediated currents can be regulated by the intracellular Ca^...

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Veröffentlicht in:Pflügers Archiv 2015-02, Vol.467 (2), p.267-284
Hauptverfasser: Toyoda, Hiroki, Saito, Mitsuru, Sato, Hajime, Tanaka, Takuma, Ogawa, Takeo, Yatani, Hirofumi, Kawano, Tsutomu, Kanematsu, Takashi, Hirata, Masato, Kang, Youngnam
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Sprache:eng
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