Measuring the impact of cognitive and psychosocial interventions in persons with mild cognitive impairment with a randomized single-blind controlled trial: rationale and design of the MEMO+ study
Several studies have suggested that cognitive training is a potentially effective way to improve cognition and postpone cognitive decline in older adults with mild cognitive impairment (MCI). The MEMO+ study is a randomized, controlled, single-blind trial designed to test the efficacy, specificity,...
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| Veröffentlicht in: | International psychogeriatrics 2015-03, Vol.27 (3), p.511-525 |
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| creator | Bier, Nathalie Grenier, Sébastien Brodeur, Catherine Gauthier, Serge Gilbert, Brigitte Hudon, Carol Lepage, Émilie Ouellet, Marie-Christine Viscogliosi, Chantal Belleville, Sylvie |
| description | Several studies have suggested that cognitive training is a potentially effective way to improve cognition and postpone cognitive decline in older adults with mild cognitive impairment (MCI). The MEMO+ study is a randomized, controlled, single-blind trial designed to test the efficacy, specificity, and long-term effect of a cognitive training intervention and a psychosocial intervention in persons with MCI.
One hundred and sixty-two participants with MCI will be recruited. They will be randomized into three groups: cognitive training, psychosocial intervention, and no-contact. Each intervention will last for eight weeks (one session per week) and a booster training session will be provided three months after the end of the intervention. Various proximal and distal outcomes will be measured at pre-intervention as well as at one week, three months, and six months post-training. Proximal outcomes include memory and psychological health measures. Distal outcomes focus on self-rated functioning in complex daily activities and strategies used in daily life to enhance function. Socio-demographic factors (age, gender, and education), general cognition, personality traits, engagement in activities, and self-efficacy will be used as moderators. Enrolment began in April 2012 and will be completed by December 2014.
This study is likely to have a significant impact on the well-being of persons with MCI by contributing to the development of adapted and scientifically supported cognitive and psychosocial interventions. |
| doi_str_mv | 10.1017/S1041610214001902 |
| format | Article |
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One hundred and sixty-two participants with MCI will be recruited. They will be randomized into three groups: cognitive training, psychosocial intervention, and no-contact. Each intervention will last for eight weeks (one session per week) and a booster training session will be provided three months after the end of the intervention. Various proximal and distal outcomes will be measured at pre-intervention as well as at one week, three months, and six months post-training. Proximal outcomes include memory and psychological health measures. Distal outcomes focus on self-rated functioning in complex daily activities and strategies used in daily life to enhance function. Socio-demographic factors (age, gender, and education), general cognition, personality traits, engagement in activities, and self-efficacy will be used as moderators. Enrolment began in April 2012 and will be completed by December 2014.
This study is likely to have a significant impact on the well-being of persons with MCI by contributing to the development of adapted and scientifically supported cognitive and psychosocial interventions.</description><identifier>ISSN: 1041-6102</identifier><identifier>EISSN: 1741-203X</identifier><identifier>DOI: 10.1017/S1041610214001902</identifier><identifier>PMID: 25268968</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Activities of Daily Living ; Aged ; Aged, 80 and over ; Canada ; Cognition ; Cognition & reasoning ; Cognitive Dysfunction - rehabilitation ; Dementia - rehabilitation ; Education ; Female ; Humans ; Intervention ; Male ; Memory ; Middle Aged ; Neuropsychological Tests ; Older people ; Patient Outcome Assessment ; Protocol-Only Paper ; Research Design ; Self Efficacy ; Single-Blind Method ; Social psychology ; Training</subject><ispartof>International psychogeriatrics, 2015-03, Vol.27 (3), p.511-525</ispartof><rights>Copyright © International Psychogeriatric Association 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c321t-ed1ddb6cfb66cf020ef59266b1fe88569ef038665f5fef9e508fbabc44a76ddc3</citedby><cites>FETCH-LOGICAL-c321t-ed1ddb6cfb66cf020ef59266b1fe88569ef038665f5fef9e508fbabc44a76ddc3</cites><orcidid>0000-0002-7554-3187</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S1041610214001902/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,315,781,785,12851,27929,27930,31004,55633</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25268968$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bier, Nathalie</creatorcontrib><creatorcontrib>Grenier, Sébastien</creatorcontrib><creatorcontrib>Brodeur, Catherine</creatorcontrib><creatorcontrib>Gauthier, Serge</creatorcontrib><creatorcontrib>Gilbert, Brigitte</creatorcontrib><creatorcontrib>Hudon, Carol</creatorcontrib><creatorcontrib>Lepage, Émilie</creatorcontrib><creatorcontrib>Ouellet, Marie-Christine</creatorcontrib><creatorcontrib>Viscogliosi, Chantal</creatorcontrib><creatorcontrib>Belleville, Sylvie</creatorcontrib><title>Measuring the impact of cognitive and psychosocial interventions in persons with mild cognitive impairment with a randomized single-blind controlled trial: rationale and design of the MEMO+ study</title><title>International psychogeriatrics</title><addtitle>Int. Psychogeriatr</addtitle><description>Several studies have suggested that cognitive training is a potentially effective way to improve cognition and postpone cognitive decline in older adults with mild cognitive impairment (MCI). The MEMO+ study is a randomized, controlled, single-blind trial designed to test the efficacy, specificity, and long-term effect of a cognitive training intervention and a psychosocial intervention in persons with MCI.
One hundred and sixty-two participants with MCI will be recruited. They will be randomized into three groups: cognitive training, psychosocial intervention, and no-contact. Each intervention will last for eight weeks (one session per week) and a booster training session will be provided three months after the end of the intervention. Various proximal and distal outcomes will be measured at pre-intervention as well as at one week, three months, and six months post-training. Proximal outcomes include memory and psychological health measures. Distal outcomes focus on self-rated functioning in complex daily activities and strategies used in daily life to enhance function. Socio-demographic factors (age, gender, and education), general cognition, personality traits, engagement in activities, and self-efficacy will be used as moderators. Enrolment began in April 2012 and will be completed by December 2014.
This study is likely to have a significant impact on the well-being of persons with MCI by contributing to the development of adapted and scientifically supported cognitive and psychosocial interventions.</description><subject>Activities of Daily Living</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Canada</subject><subject>Cognition</subject><subject>Cognition & reasoning</subject><subject>Cognitive Dysfunction - rehabilitation</subject><subject>Dementia - rehabilitation</subject><subject>Education</subject><subject>Female</subject><subject>Humans</subject><subject>Intervention</subject><subject>Male</subject><subject>Memory</subject><subject>Middle Aged</subject><subject>Neuropsychological Tests</subject><subject>Older people</subject><subject>Patient Outcome Assessment</subject><subject>Protocol-Only Paper</subject><subject>Research Design</subject><subject>Self Efficacy</subject><subject>Single-Blind Method</subject><subject>Social psychology</subject><subject>Training</subject><issn>1041-6102</issn><issn>1741-203X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkk2LFDEQhhtR3HX1B3iRgBdBWvPRSXd7k2X9gB32oIK3Jp1UZrKkkzZJr4x_zz9m2hllUcRLUkk971sVUlX1mOAXBJP25QeCGyIIpqTBmPSY3qlOSduQmmL2-W6JS7pe8yfVg5SuMaackeZ-dUI5FV0vutPq-wZkWqL1W5R3gOw0S5VRMEiFrbfZ3gCSXqM57dUupKCsdMj6DPEGfLbBp3JCM8S0hl9t3qHJOn1LvTraOBX6kJYoFsMw2W-gUSp1HdSjs37V-ByDc-U-x1LnVSHXEtIdetCQ7Navva2dbi42V89RyoveP6zuGekSPDruZ9WnNxcfz9_Vl1dv35-_vqwVoyTXoInWo1BmFGXBFIPhPRViJAa6joseDGadENxwA6YHjjszylE1jWyF1oqdVc8OvnMMXxZIeZhsUuCc9BCWNJCWM477lrL_o4LTpml50xX06R_odVhiefVPCuO-axkpFDlQKoaUIphhjnaScT8QPKzDMPw1DEXz5Oi8jBPo34pfv18AdjSV0xit3sKt2v-0_QHJ-cL4</recordid><startdate>201503</startdate><enddate>201503</enddate><creator>Bier, Nathalie</creator><creator>Grenier, Sébastien</creator><creator>Brodeur, Catherine</creator><creator>Gauthier, Serge</creator><creator>Gilbert, Brigitte</creator><creator>Hudon, Carol</creator><creator>Lepage, Émilie</creator><creator>Ouellet, Marie-Christine</creator><creator>Viscogliosi, Chantal</creator><creator>Belleville, Sylvie</creator><general>Cambridge University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88J</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2R</scope><scope>M2S</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>7TK</scope><orcidid>https://orcid.org/0000-0002-7554-3187</orcidid></search><sort><creationdate>201503</creationdate><title>Measuring the impact of cognitive and psychosocial interventions in persons with mild cognitive impairment with a randomized single-blind controlled trial: rationale and design of the MEMO+ study</title><author>Bier, Nathalie ; Grenier, Sébastien ; Brodeur, Catherine ; Gauthier, Serge ; Gilbert, Brigitte ; Hudon, Carol ; Lepage, Émilie ; Ouellet, Marie-Christine ; Viscogliosi, Chantal ; Belleville, Sylvie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c321t-ed1ddb6cfb66cf020ef59266b1fe88569ef038665f5fef9e508fbabc44a76ddc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Activities of Daily Living</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Canada</topic><topic>Cognition</topic><topic>Cognition & reasoning</topic><topic>Cognitive Dysfunction - rehabilitation</topic><topic>Dementia - rehabilitation</topic><topic>Education</topic><topic>Female</topic><topic>Humans</topic><topic>Intervention</topic><topic>Male</topic><topic>Memory</topic><topic>Middle Aged</topic><topic>Neuropsychological Tests</topic><topic>Older people</topic><topic>Patient Outcome Assessment</topic><topic>Protocol-Only Paper</topic><topic>Research Design</topic><topic>Self Efficacy</topic><topic>Single-Blind Method</topic><topic>Social psychology</topic><topic>Training</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bier, Nathalie</creatorcontrib><creatorcontrib>Grenier, Sébastien</creatorcontrib><creatorcontrib>Brodeur, Catherine</creatorcontrib><creatorcontrib>Gauthier, Serge</creatorcontrib><creatorcontrib>Gilbert, Brigitte</creatorcontrib><creatorcontrib>Hudon, Carol</creatorcontrib><creatorcontrib>Lepage, Émilie</creatorcontrib><creatorcontrib>Ouellet, Marie-Christine</creatorcontrib><creatorcontrib>Viscogliosi, Chantal</creatorcontrib><creatorcontrib>Belleville, Sylvie</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Sociology Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Social Science Database</collection><collection>Sociology Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>International psychogeriatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bier, Nathalie</au><au>Grenier, Sébastien</au><au>Brodeur, Catherine</au><au>Gauthier, Serge</au><au>Gilbert, Brigitte</au><au>Hudon, Carol</au><au>Lepage, Émilie</au><au>Ouellet, Marie-Christine</au><au>Viscogliosi, Chantal</au><au>Belleville, Sylvie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Measuring the impact of cognitive and psychosocial interventions in persons with mild cognitive impairment with a randomized single-blind controlled trial: rationale and design of the MEMO+ study</atitle><jtitle>International psychogeriatrics</jtitle><addtitle>Int. Psychogeriatr</addtitle><date>2015-03</date><risdate>2015</risdate><volume>27</volume><issue>3</issue><spage>511</spage><epage>525</epage><pages>511-525</pages><issn>1041-6102</issn><eissn>1741-203X</eissn><abstract>Several studies have suggested that cognitive training is a potentially effective way to improve cognition and postpone cognitive decline in older adults with mild cognitive impairment (MCI). The MEMO+ study is a randomized, controlled, single-blind trial designed to test the efficacy, specificity, and long-term effect of a cognitive training intervention and a psychosocial intervention in persons with MCI.
One hundred and sixty-two participants with MCI will be recruited. They will be randomized into three groups: cognitive training, psychosocial intervention, and no-contact. Each intervention will last for eight weeks (one session per week) and a booster training session will be provided three months after the end of the intervention. Various proximal and distal outcomes will be measured at pre-intervention as well as at one week, three months, and six months post-training. Proximal outcomes include memory and psychological health measures. Distal outcomes focus on self-rated functioning in complex daily activities and strategies used in daily life to enhance function. Socio-demographic factors (age, gender, and education), general cognition, personality traits, engagement in activities, and self-efficacy will be used as moderators. Enrolment began in April 2012 and will be completed by December 2014.
This study is likely to have a significant impact on the well-being of persons with MCI by contributing to the development of adapted and scientifically supported cognitive and psychosocial interventions.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>25268968</pmid><doi>10.1017/S1041610214001902</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0002-7554-3187</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1041-6102 |
| ispartof | International psychogeriatrics, 2015-03, Vol.27 (3), p.511-525 |
| issn | 1041-6102 1741-203X |
| language | eng |
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| source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); Cambridge University Press Journals Complete |
| subjects | Activities of Daily Living Aged Aged, 80 and over Canada Cognition Cognition & reasoning Cognitive Dysfunction - rehabilitation Dementia - rehabilitation Education Female Humans Intervention Male Memory Middle Aged Neuropsychological Tests Older people Patient Outcome Assessment Protocol-Only Paper Research Design Self Efficacy Single-Blind Method Social psychology Training |
| title | Measuring the impact of cognitive and psychosocial interventions in persons with mild cognitive impairment with a randomized single-blind controlled trial: rationale and design of the MEMO+ study |
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