Normal nerve striations are altered in the trembler-J mouse, a model of charcot-marie-tooth disease

ABSTRACT Introduction: This study was initiated because it was noted that the peripheral nerves of Trembler‐J mice (a model of human Charcot–Marie–Tooth disease) appear to lack normal striations. Methods: We performed confocal microscopy of whole sciatic nerves and tested the effect of axial stress...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Muscle & nerve 2015-02, Vol.51 (2), p.246-252
Hauptverfasser:	Power, Bridget J., O'reilly, Gavin, Murphy, Robert, Murphy, Keith J., Pickering, Mark, Jones, James F.X.
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Animals Axons - pathology bands of Fontana Charcot-Marie-Tooth disease Charcot-Marie-Tooth Disease - genetics Charcot-Marie-Tooth Disease - metabolism Charcot-Marie-Tooth Disease - pathology Disease Models, Animal Electrophysiology Male Medical research Mice Mice, Inbred C57BL Mice, Neurologic Mutants Microscopy, Confocal Mutation - genetics Myelin Proteins - genetics Myelin Sheath - metabolism Myelin Sheath - pathology nerve stretch Neural Conduction - genetics Neural Conduction - physiology rat Rodents sciatic nerve Sciatic Nerve - metabolism Sciatic Nerve - physiopathology Stress, Mechanical
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!