Comparative study on toxic effects induced by oral or intravascular administration of commonly used disinfectants and surfactants in rats

ABSTRACT Accidental ingestion or injection of household products sometimes occurs due to their accessibility, but the toxic manifestations have not been well characterized when they are internally administered. The aim of this study was to investigate the toxic effects induced by ingestion or inject...

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Veröffentlicht in:	Journal of applied toxicology 2012-07, Vol.32 (7), p.480-487
Hauptverfasser:	Xue, Yuying, Zhang, Shanshan, Tang, Meng, Zhang, Ting, Wang, Yiqing, Hieda, Yoko, Takeshita, Haruo
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Amphoterics Animals Benzalkonium Compounds - administration & dosage Benzalkonium Compounds - toxicity Benzethonium - administration & dosage Benzethonium - toxicity Biological and medical sciences Cationic Cetomacrogol - administration & dosage Chlorhexidine - administration & dosage Chlorhexidine - toxicity disinfectant Disinfectants - administration & dosage Disinfectants - toxicity Domestic and cosmetic products toxicology Dose-Response Relationship, Drug Ingestion Injections, Intravenous intravascular administration Kidney - drug effects Kidney - metabolism kinetics Lethal Dose 50 Lung - drug effects Lung - metabolism Male Medical sciences Nonionic oral administration Rats Rats, Sprague-Dawley Surface-Active Agents - administration & dosage Surface-Active Agents - toxicity surfactant Surfactants Toxic toxic effects Toxicology
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