Genetic polymorphism of pri-microRNA 325, targeting SLC6A4 3′-UTR, is closely associated with the risk of functional dyspepsia in Japan

Background The role of genetics in the susceptibility to functional dyspepsia (FD) remains unclear. We attempted to clarify the association between FD and polymorphisms in SLC6A4 . In addition, rs5981521 (C>T) in the pri-microRNA 325 (pri-miR-325) coding region was also investigated. Methods The...

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Veröffentlicht in:	Journal of gastroenterology 2012-10, Vol.47 (10), p.1091-1098
Hauptverfasser:	Arisawa, Tomiyasu, Tahara, Tomomitsu, Fukuyama, Tomoki, Hayashi, Ranji, Matsunaga, Kazuhiro, Hayashi, Nobuhiko, Nakamura, Masakatsu, Toshikuni, Nobuyuki, Shiroeda, Hisakazu, Shibata, Tomoyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Adult Aged Aged, 80 and over Colorectal Surgery Dyspepsia Dyspepsia - genetics Dyspepsia - microbiology Female Gastroenterology Genetic aspects Genetic polymorphisms Genetic Predisposition to Disease Genetic research Helicobacter Helicobacter pylori - isolation & purification Hepatology Humans Japan Male Medicine Medicine & Public Health MicroRNA MicroRNAs - genetics Middle Aged Original Article—Alimentary Tract Polymerase Chain Reaction Polymorphism, Genetic Polymorphism, Single-Stranded Conformational Risk Factors Serotonin Plasma Membrane Transport Proteins - genetics Surgical Oncology Untranslated Regions
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