Diffusive Nature of Xenon Anesthetic Changes Properties of a Lipid Bilayer: Molecular Dynamics Simulations

Effects of general anesthesia can be controllable by the ambient pressure. We perform molecular dynamics simulations for a 1-palmitoyl-2-oleoyl phosphatidylethanolamine lipid bilayer with or without xenon molecules by changing the pressure to elucidate the mechanism of the pressure reversal of gener...

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Veröffentlicht in:	The journal of physical chemistry. B 2012-08, Vol.116 (30), p.8989-8995
Hauptverfasser:	Yamamoto, Eiji, Akimoto, Takuma, Shimizu, Hiroyuki, Hirano, Yoshinori, Yasui, Masato, Yasuoka, Kenji
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Diffusion Diffusivity Lipid Bilayers - chemistry Lipid Bilayers - metabolism Lipids Molecular dynamics Molecular Dynamics Simulation Phosphatidylethanolamines - chemistry Pressure Pushing Simulation Xenon Xenon - chemistry
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