6-Thioguanine measurement allows optimisation in management of IBD patients on azathioprine

Introduction Azathioprine is widely used in the management of Inflammatory Bowel Disease (IBD). The ideal dose for a patient is usually calculated by weight, but the rate of metabolism of azathioprine to its active metabolite 6-thioguanine (6TGN) varies between individuals. In addition, therapy may...

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Veröffentlicht in:	Gut 2011-04, Vol.60 (Suppl 1), p.A141-A141
Hauptverfasser:	Dolman, G E, Johnson, H E, McLaughlin, S D, Begley, J P, Weaver, S A
Format:	Artikel
Sprache:	eng
Schlagworte:	6-thioguanine Azathioprine Crohn's disease Demography Disease management Inflammatory bowel disease Inflammatory bowel diseases Intestine Liver Metabolism Metabolites Patients Surgery Thioguanine thiopurine Ulcerative colitis
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