Theoretical Considerations of the Prigogine–Defay Ratio with Regard to the Glass-Forming Ability of Drugs from Undercooled Melts

Drug behavior in undercooled melts is highly important for pharmaceutics with regard to amorphous solid dispersions, and therefore, categories were recently introduced that differentiate glass formers (GFs) from other drugs that are nonglass formers (nGFs). The present study is based on the assumpti...

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Veröffentlicht in:	Molecular pharmaceutics 2016-01, Vol.13 (1), p.241-250
Hauptverfasser:	Wyttenbach, Nicole, Kirchmeyer, Wiebke, Alsenz, Jochem, Kuentz, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry, Pharmaceutical - methods Computer Simulation Crystallization Drug Stability Glass - chemistry Hydrogen Bonding Transition Temperature
Online-Zugang:	Volltext
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