Application of 3‑Methyl-2-vinylindoles in Catalytic Asymmetric Povarov Reaction: Diastereo- and Enantioselective Synthesis of Indole-Derived Tetrahydroquinolines

The first application of 3-methyl-2-vinylindoles in catalytic asymmetric Povarov reactions has been established via the three-component reactions of 3-methyl-2-vinylindoles, aldehydes, and anilines in the presence of chiral phosphoric acid, providing easy access to chiral indole-derived tetrahydroqu...

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Veröffentlicht in:Journal of organic chemistry 2016-01, Vol.81 (1), p.185-192
Hauptverfasser: Dai, Wei, Jiang, Xiao-Li, Tao, Ji-Yu, Shi, Feng
Format: Artikel
Sprache:eng
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