Enantiomeric composition of N′-nitrosonornicotine and N′-nitrosoanatabine in tobacco

The tobacco-specific nitrosamines N′-nitrosonornicotine (NNN) and N′-nitrosoanatabine (NAT) are found in substantial quantities in unburned tobacco. Although this has been documented in many previous studies, no data are available on the enantiomeric composition of these nitrosamines, which both hav...

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Veröffentlicht in:	Carcinogenesis (New York) 2000-04, Vol.21 (4), p.839-843
Hauptverfasser:	Carmella, Steven G., McIntee, Edward J., Chen, Menglan, Hecht, Stephen S.
Format:	Artikel
Sprache:	eng
Schlagworte:	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone 5-MeNNN 5-methyl-N′-nitrosonornicotine Biological and medical sciences Carcinogens - analysis Chromatography, Gas Chromatography, High Pressure Liquid gas chromatography with detection by thermal energy analyzer gas chromatography–mass spectrometry with selected ion monitoring GC-MS-SIM GC-TEA Medical sciences N'-Nitrosoanatabine N'-Nitrosonornicotine NAB NAT Nicotiana - chemistry Nitrosamines - analysis NNK NNN N′-nitrosoanabasine Plants, Toxic Stereoisomerism Tobacco, tobacco smoking Toxicology
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