Association between parental history and genetic risk scores for coronary heart disease prediction: The population-based CoLaus study

Abstract Background and Aims Parental history (PH) and genetic risk scores (GRSs) are separately associated with coronary heart disease (CHD), but evidence regarding their combined effects is lacking. We aimed to evaluate the joint associations and predictive ability of PH and GRSs for incident CHD....

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Veröffentlicht in:	Atherosclerosis 2016-01, Vol.244, p.59-65
Hauptverfasser:	Antiochos, Panagiotis, Marques-Vidal, Pedro, McDaid, Aaron, Waeber, Gerard, Vollenweider, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiovascular Coronary Artery Disease - diagnosis Coronary Artery Disease - epidemiology Coronary Artery Disease - genetics Coronary heart disease Female Follow-Up Studies Genetic Predisposition to Disease Genetic risk score Genome-Wide Association Study Humans Incidence Male Middle Aged Parental history Parents Population Surveillance Prospective Studies Prospective study Reclassification Risk Factors Switzerland - epidemiology
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