Role of dopamine in prepulse inhibition of acoustic startle

Prepulse inhibition of acoustic startle is the reduction in startle response to an intense auditory stimulus when this stimulus is immediately preceded by a weaker prestimulus. Prepulse inhibition occurs normally in humans and experimental animals, but schizophrenic persons often exhibit a marked im...

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Veröffentlicht in:	Psychopharmacologia 2000-04, Vol.149 (2), p.181-188
Hauptverfasser:	JIANHUA ZHANG, FORKSTAM, C, ENGEL, J. A, SVENSSON, L
Format:	Artikel
Sprache:	eng
Schlagworte:	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - pharmacology Acoustic Stimulation Agonists Amphetamine - pharmacology Amphetamines Analysis of Variance Animals Antipsychotics Biological and medical sciences Catecholaminergic system Cocaine Cocaine - pharmacology Dopamine Dopamine - physiology Dopamine Agonists - pharmacology Dopamine Antagonists - pharmacology Dopamine D1 receptors Dopamine D2 Receptor Antagonists Dopamine D2 receptors Male Medical sciences Neuromodulation Neuropharmacology Neurotransmission Neurotransmitters. Neurotransmission. Receptors Noise Nucleus accumbens Pharmacology. Drug treatments Quinpirole Quinpirole - pharmacology Raclopride Raclopride - pharmacology Rats Rats, Sprague-Dawley Receptors, Dopamine D1 - agonists Receptors, Dopamine D1 - metabolism Receptors, Dopamine D2 - agonists Receptors, Dopamine D2 - metabolism Reflex, Startle - drug effects Reflex, Startle - physiology Startle response
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