Effect of polymorphisms in the GBP1, Mx1 and CD163 genes on host responses to PRRSV infection in pigs

•Viremia levels and weight gains were good parameters for host resistance to PRRS.•Polymorphisms in GBP1 were associated with host resistance to PRRS.•T cell activation was significantly correlated with viremia and weight gains.•Polymorphisms in GBP1 were associated with enhanced levels of T cell ac...

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Veröffentlicht in:	Veterinary microbiology 2016-01, Vol.182, p.187-195
Hauptverfasser:	Niu, Pengxia, Shabir, Nadeem, Khatun, Amina, Seo, Byoung-Joo, Gu, Suna, Lee, Sang-Myoung, Lim, Si-Kyu, Kim, Kwan-Suk, Kim, Won-Il
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - genetics Antigens, CD - immunology Antigens, Differentiation, Myelomonocytic - genetics Antigens, Differentiation, Myelomonocytic - immunology CD163 GBP1 Genotype GTP-Binding Proteins - genetics GTP-Binding Proteins - immunology Host-Pathogen Interactions - genetics Host-Pathogen Interactions - immunology Immune response Lymphocyte Activation Mx1 Myxovirus Resistance Proteins - genetics Myxovirus Resistance Proteins - immunology Pig Polymorphism, Genetic Porcine Reproductive and Respiratory Syndrome - genetics Porcine Reproductive and Respiratory Syndrome - immunology Porcine respiratory and reproductive syndrome virus - immunology PRRSV Receptors, Cell Surface - genetics Receptors, Cell Surface - immunology Swine T-Lymphocytes - immunology Viremia - genetics Viremia - immunology Weight Gain
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