Cruciferous phytoalexins: antiproliferative effects in T-Jurkat leukemic cells

We tested antiproliferative activity of selected cruciferous phytoalexins including brassinin, 1-methoxybrassinin, (±)-spirobrassin, (±)-1-methoxyspirobrassinin and (±)-1-methoxyspirobrassinol, in leukemic Jurkat cell. The most effective of the tested phytoalexins was 1-methoxybrassinin with IC 50 1...

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Veröffentlicht in:	Leukemia research 2005-04, Vol.29 (4), p.415-421
Hauptverfasser:	Pilátová, M., Šarišský, M., Kutschy, P., Miroššay, A., Mezencev, R., Čurillová, Z., Suchý, M., Monde, K., Mirossay, L., Mojžiš, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiproliferative effects Apoptosis Apoptosis - drug effects Brassicaceae Cell Death - drug effects Cruciferous phytoalexins Dose-Response Relationship, Drug Humans Jurkat Cells - drug effects Leukemia Phytotherapy Plant Extracts - toxicity Sesquiterpenes Terpenes
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