Development of a Sustained Release Solid Dispersion Using Swellable Polymer by Melting Method

Purpose This study is to design a sustained release solid dispersion using swellable polymer by melting method. Methods Polyethylene glycol 6000 (PEG 6000) and hydroxypropyl methylcellulose 4000 (HPMC 4000) were used in solid dispersion for not only enhancing drug dissolution rate but also sustainin...

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Veröffentlicht in:	Pharmaceutical research 2016-01, Vol.33 (1), p.102-109
Hauptverfasser:	Nguyen, Tuong Ngoc-Gia, Tran, Phuong Ha-Lien, Van Vo, Toi, Duan, Wei, Truong-Dinh Tran, Thao
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Chemistry, Pharmaceutical Communications industry Delayed-Action Preparations Dispersion Drug delivery systems Drug Design Hypromellose Derivatives - chemistry Medical Law Methods Methylcellulose Patient compliance Pharmaceutical sciences Pharmacology/Toxicology Pharmacy Polyethylene Glycols - chemistry Polymer industry Polymers Research Paper Solubility Tablets Telecommunications services industry X-Ray Diffraction
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