Breakthrough pain and its treatment: critical review and recommendations of IOPS (Italian Oncologic Pain Survey) expert group
Controversies exist about the definition and epidemiology of breakthrough cancer pain (BTcP), the pharmacological treatment options, drug dosing, and how to select the medications for BTcP among the new fentanyl products. Existing data were critically evaluated to provide recommendations by an exper...
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Veröffentlicht in: | Supportive care in cancer 2016-02, Vol.24 (2), p.961-968 |
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creator | Mercadante, Sebastiano Marchetti, Paolo Cuomo, Arturo Mammucari, Massimo Caraceni, Augusto |
description | Controversies exist about the definition and epidemiology of breakthrough cancer pain (BTcP), the pharmacological treatment options, drug dosing, and how to select the medications for BTcP among the new fentanyl products. Existing data were critically evaluated to provide recommendations by an expert group. An algorithm to diagnose BTcP should be used followed by a careful assessment. Fentanyl products provide efficacy and rapidity of action to counteract the temporal pattern of BTcP. The doses of opioids used for background pain should guide the choice of the doses of fentanyl products. The choice of fentanyl products should be based on individual clinical conditions. |
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Existing data were critically evaluated to provide recommendations by an expert group. An algorithm to diagnose BTcP should be used followed by a careful assessment. Fentanyl products provide efficacy and rapidity of action to counteract the temporal pattern of BTcP. The doses of opioids used for background pain should guide the choice of the doses of fentanyl products. 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Existing data were critically evaluated to provide recommendations by an expert group. An algorithm to diagnose BTcP should be used followed by a careful assessment. Fentanyl products provide efficacy and rapidity of action to counteract the temporal pattern of BTcP. The doses of opioids used for background pain should guide the choice of the doses of fentanyl products. 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methods</subject><subject>Pain Medicine</subject><subject>Rehabilitation Medicine</subject><subject>Review Article</subject><subject>Surveys</subject><subject>Surveys and Questionnaires</subject><issn>0941-4355</issn><issn>1433-7339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kV1vFCEYhYnR2G31B3hjSLxpL6bCAMOMd7XxY5Mm26R6TVh4Z0qdgRWY6l7432W79TMaLkg4zzm8cBB6RskpJUS-TISImlSEiqruBK22D9CCcsYqyVj3EC1Ix2nFmRAH6DClG0KolKJ-jA7qhrOWcrFA315H0J_ydQzzcI032nmsvcUuJ5yLkifw-RU20WVn9Igj3Dr4codEMGEqstXZBZ9w6PFydXmFj5dZj057vPImjGFwBl_uYq_meAvbEwxfNxAzHsqNmyfoUa_HBE_v9yP08e2bD-fvq4vVu-X52UVlBBO5sqZmnW1brRu7Jo0FY3hDuZS2tqxtjVwb1sleALedEVJb0QtpetoA1X3b1OwIHe9zNzF8niFlNblkYBy1hzAnRaWgXVf-khf0xV_oTZijL9PdUUzWUjS_qEGPoJzvQ47a7ELVGed12xFOukKd_oMqy8LkTPDQu3L-h4HuDSaGlCL0ahPdpONWUaJ2lat95apUrnaVq23xPL8feF5PYH86fnRcgHoPpCL5AeJvL_pv6nfUsban</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Mercadante, Sebastiano</creator><creator>Marchetti, Paolo</creator><creator>Cuomo, Arturo</creator><creator>Mammucari, Massimo</creator><creator>Caraceni, Augusto</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88J</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2R</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20160201</creationdate><title>Breakthrough pain and its treatment: critical review and recommendations of IOPS (Italian Oncologic Pain Survey) expert group</title><author>Mercadante, Sebastiano ; Marchetti, Paolo ; Cuomo, Arturo ; Mammucari, Massimo ; Caraceni, Augusto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c535t-dc239d88aa6db06decc461477d2d388c7bc397f5e4d9c57ad5f57cf16e1af8623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Algorithms</topic><topic>Analgesics, Opioid - 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subjects | Algorithms Analgesics, Opioid - administration & dosage Analgesics, Opioid - therapeutic use Breakthrough Pain - drug therapy Cancer Care and treatment Choice Behavior Epidemiology Ethnic Groups Evidence-based medicine Expert Testimony Fentanyl - administration & dosage Fentanyl - therapeutic use Humans Italy Medicine Medicine & Public Health Narcotics Neoplasms - drug therapy Nursing Nursing Research Oncology Opioids Pain Pain management Pain Measurement - methods Pain Medicine Rehabilitation Medicine Review Article Surveys Surveys and Questionnaires |
title | Breakthrough pain and its treatment: critical review and recommendations of IOPS (Italian Oncologic Pain Survey) expert group |
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