Breakthrough pain and its treatment: critical review and recommendations of IOPS (Italian Oncologic Pain Survey) expert group

Controversies exist about the definition and epidemiology of breakthrough cancer pain (BTcP), the pharmacological treatment options, drug dosing, and how to select the medications for BTcP among the new fentanyl products. Existing data were critically evaluated to provide recommendations by an exper...

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Veröffentlicht in:Supportive care in cancer 2016-02, Vol.24 (2), p.961-968
Hauptverfasser: Mercadante, Sebastiano, Marchetti, Paolo, Cuomo, Arturo, Mammucari, Massimo, Caraceni, Augusto
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container_issue 2
container_start_page 961
container_title Supportive care in cancer
container_volume 24
creator Mercadante, Sebastiano
Marchetti, Paolo
Cuomo, Arturo
Mammucari, Massimo
Caraceni, Augusto
description Controversies exist about the definition and epidemiology of breakthrough cancer pain (BTcP), the pharmacological treatment options, drug dosing, and how to select the medications for BTcP among the new fentanyl products. Existing data were critically evaluated to provide recommendations by an expert group. An algorithm to diagnose BTcP should be used followed by a careful assessment. Fentanyl products provide efficacy and rapidity of action to counteract the temporal pattern of BTcP. The doses of opioids used for background pain should guide the choice of the doses of fentanyl products. The choice of fentanyl products should be based on individual clinical conditions.
doi_str_mv 10.1007/s00520-015-2951-y
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source MEDLINE; SpringerNature Journals
subjects Algorithms
Analgesics, Opioid - administration & dosage
Analgesics, Opioid - therapeutic use
Breakthrough Pain - drug therapy
Cancer
Care and treatment
Choice Behavior
Epidemiology
Ethnic Groups
Evidence-based medicine
Expert Testimony
Fentanyl - administration & dosage
Fentanyl - therapeutic use
Humans
Italy
Medicine
Medicine & Public Health
Narcotics
Neoplasms - drug therapy
Nursing
Nursing Research
Oncology
Opioids
Pain
Pain management
Pain Measurement - methods
Pain Medicine
Rehabilitation Medicine
Review Article
Surveys
Surveys and Questionnaires
title Breakthrough pain and its treatment: critical review and recommendations of IOPS (Italian Oncologic Pain Survey) expert group
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