Increasing DNA reactivity and in vitro antitumor activity of trans diiodido Pt(II) complexes with UVA light

Trans diiodido platinum(II) complexes bearing the same as well as different aliphatic amines (mixed-amines) have interesting biological activity; cytotoxicity and interactions with some important biological models have already been demonstrated. Herein we described the interaction of such compounds...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of inorganic biochemistry 2015-12, Vol.153, p.211-218
Hauptverfasser:	Navas, Francisco, Perfahl, Stefanie, Garino, Claudio, Salassa, Luca, Novakova, Olga, Navarro-Ranninger, Carmen, Bednarski, Patrick J., Malina, Jaroslav, Quiroga, Adoración.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Antineoplastic Agents - radiation effects Antineoplastic Agents - toxicity Cell Line, Tumor DNA - chemistry DNA interactions Humans Iodides - chemistry Metallodrug photoactivaton Organoplatinum Compounds - chemistry Organoplatinum Compounds - radiation effects Organoplatinum Compounds - toxicity Platinum drugs Ultraviolet Rays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!