The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BK sub(Ca) channels

Female sexual function is under-studied, and mechanisms of clitoral engorgement-relaxation are incompletely understood. Penile erection results from nitric oxide (NO)-induced cyclic guanosine monophosphate (cGMP) accumulation. cGMP-dependent protein kinase (PKG) activates large-conductance, calcium-...

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Veröffentlicht in:The FASEB journal 2004-09, Vol.18 (12), p.1382-1391
Hauptverfasser: Gragasin, Ferrante S, Michelakis, Evangelos D, Hogan, Angie, Moudgil, Rohit, Hashimoto, Kyoko, Wu, Xichen, Bonnet, Sandra, Haromy, Al, Archer, Stephen L
Format: Artikel
Sprache:eng
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