Annexin A1 Is a Key Modulator of Mesenchymal Stromal Cell-Mediated Improvements in Islet Function

We have previously demonstrated that coculture of islets with mesenchymal stromal cells (MSCs) enhanced islet insulin secretory capacity in vitro, correlating with improved graft function in vivo. To identify factors that contribute to MSC-mediated improvements in islet function, we have used an unb...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2016-01, Vol.65 (1), p.129-139
Hauptverfasser:	Rackham, Chloe L, Vargas, Andreia E, Hawkes, Ross G, Amisten, Stefan, Persaud, Shanta J, Austin, Amazon L F, King, Aileen J F, Jones, Peter M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Annexin A1 - genetics Annexin A1 - metabolism Blood Glucose - metabolism Blotting, Western Coculture Techniques Diabetes Diabetes Mellitus, Experimental - genetics Diabetes Mellitus, Experimental - metabolism Enzyme-Linked Immunosorbent Assay Gene expression Gene Knockdown Techniques Glucose In Vitro Techniques Insulin - metabolism Insulin Secretion Islets of Langerhans - metabolism Ligands Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells - metabolism Mice Real-Time Polymerase Chain Reaction RNA, Messenger - metabolism RNA, Small Interfering Rodents
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!