One-step detection of pathogens and cancer biomarkers by the naked eye based on aggregation of immunomagnetic beads

This report shows that immunomagnetic beads (IMBs) can act as the optical readout for assays, in addition to serving as the carrier for purification/separation. Under the influence of an external magnet, IMBs are attracted to coat one side of a test tube. IMBs specifically bound to targets can form...

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Veröffentlicht in:	Nanoscale 2016-01, Vol.8 (2), p.11-117
Hauptverfasser:	Chen, Yiping, Xianyu, Yunlei, Sun, Jiashu, Niu, Yajing, Wang, Yu, Jiang, Xingyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying Beads Biomarkers Biomarkers, Tumor - metabolism Coating Color Enzyme-Linked Immunosorbent Assay - methods Escherichia coli - isolation & purification Eyes Humans Immunomagnetic Separation - methods Magnetics Nanotechnology - methods Neoplasms - diagnosis Neoplasms - genetics Optics and Photonics Pathogens Point-of-Care Systems Salmonella - isolation & purification Shigella - isolation & purification Spirillum - isolation & purification Staphylococcus aureus - isolation & purification Stress, Mechanical Tubes
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