The significance of aberrant crypt foci in understanding the pathogenesis of colon cancer

Animal models provide a unique opportunity to study the biology of the disease process, and to test hypotheses linking environmental factors in the etiology and prevention of colon cancer. The concept of cancer prevention is to retard, regress or eliminate precancerous lesions. To actuate this conce...

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Veröffentlicht in:	Toxicology letters 2000-03, Vol.112 (1-3), p.395-402
Hauptverfasser:	Bird, Ranjana P., Good, Carolyn K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberrant crypt foci Animals Biomarkers Biomarkers, Tumor Choristoma - pathology Colon carcinogenesis Colonic Neoplasms - etiology Colonic Neoplasms - pathology Diet Disease Models, Animal Male Neoplasms, Experimental - chemically induced Neoplasms, Experimental - pathology Rats Rats, Sprague-Dawley
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