Suppression of SAMSN1 Expression is Associated with the Malignant Phenotype of Hepatocellular Carcinoma

Background Identification of molecular markers for sensitive detection of hepatocellular carcinoma (HCC) is required to achieve efficacious personalized therapy. Methods We focused here on SAM domain, SH3 domain, and nuclear localization signals 1 ( SAMSN1 ) and investigated expression and methylati...

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Veröffentlicht in:	Annals of surgical oncology 2015-12, Vol.22 (Suppl 3), p.1453-1460
Hauptverfasser:	Sueoka, Satoshi, Kanda, Mitsuro, Sugimoto, Hiroyuki, Shimizu, Dai, Nomoto, Shuji, Oya, Hisaharu, Takami, Hideki, Ezaka, Kazuhiro, Hashimoto, Ryoji, Tanaka, Yuri, Okamura, Yukiyasu, Yamada, Suguru, Fujii, Tsutomu, Nakayama, Goro, Koike, Masahiko, Fujiwara, Michitaka, Kodera, Yasuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Vesicular Transport - genetics Adaptor Proteins, Vesicular Transport - metabolism Aged Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Carcinoma, Hepatocellular - surgery Case-Control Studies Disease Progression DNA Methylation Female Follow-Up Studies Gene Expression Regulation, Neoplastic Humans Immunoenzyme Techniques Liver Neoplasms - genetics Liver Neoplasms - metabolism Liver Neoplasms - pathology Liver Neoplasms - surgery Male Medicine Medicine & Public Health Neoplasm Invasiveness Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - metabolism Neoplasm Recurrence, Local - pathology Neoplasm Recurrence, Local - surgery Neoplasm Staging Oncology Phenotype Prognosis Promoter Regions, Genetic - genetics Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Surgery Surgical Oncology Survival Rate Translational Research and Biomarkers Tumor Cells, Cultured
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