Inhibitory effects of tetrandrine on epidermal growth factor-induced invasion and migration in HT29 human colorectal adenocarcinoma cells

Tetrandrine has been shown to reduce cancer cell proliferation and to inhibit metastatic effects in multiple cancer models in vitro and in vivo. However, the effects of tetrandrine on the underlying mechanism of HT29 human colorectal adenocarcinoma cell metastasis remain to be fully elucidated. The...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular medicine reports 2016-01, Vol.13 (1), p.1003-1009
Hauptverfasser:	HORNG, CHI-TING, YANG, JAI-SING, CHIANG, JO-HUA, LU, CHI-CHENG, LEE, CHIU-FANG, CHIANG, NI-NA, CHEN, FU-AN
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Adenocarcinoma Adenocarcinoma - drug therapy Adenocarcinoma - genetics Adenocarcinoma - pathology AKT protein Angiogenesis Apoptosis Autophagy Benzylisoquinolines - administration & dosage Brain cancer Breast cancer Cell adhesion & migration Cell growth Cell Movement - drug effects Cell proliferation Cell Proliferation - drug effects Colorectal cancer Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Enzymatic activity Epidermal growth factor Epidermal Growth Factor - administration & dosage epidermal growth factor receptor Epidermal growth factor receptors Gelatin Gelatinase Gelatinase A Gelatinase B Gene expression Gene Expression Regulation, Neoplastic - drug effects HT29 Cells HT29 colorectal adenocarcinoma cells Humans Immunoblotting Immunoglobulins Kinases Ligands Lung cancer MAP kinase matrix metalloprotease-2/-9 Matrix metalloproteinase Matrix Metalloproteinase 2 - biosynthesis Matrix Metalloproteinase 9 - biosynthesis Matrix Metalloproteinase 9 - genetics Metalloproteinase Metastases Metastasis Neoplasm Invasiveness - genetics Penicillin Phosphatidylinositol 3-Kinases - biosynthesis Phosphatidylinositol 3-Kinases - genetics Phosphorylation Protein kinase Proteins Receptor, Epidermal Growth Factor - genetics Signal Transduction - drug effects tetrandrine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!