Evolutionary Stability of Minimal Mutation Rates in an Evo-epidemiological Model

We consider the evolution of mutation rate in a seasonally forced, deterministic, compartmental epidemiological model with a transmission–virulence trade-off. We model virulence as a quantitative genetic trait in a haploid population and mutation as continuous diffusion in the trait space. There is...

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Veröffentlicht in:	Bulletin of mathematical biology 2015-11, Vol.77 (11), p.1985-2003
Hauptverfasser:	Birch, Michael, Bolker, Benjamin M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Biology Host-Parasite Interactions - genetics Humans Life Sciences Mathematical and Computational Biology Mathematical Concepts Mathematics Mathematics and Statistics Models, Genetic Molecular Epidemiology Mutation Rate Original Article Virulence - genetics
Online-Zugang:	Volltext
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