Transcription factor co‐occupied regions in the murine genome constitute T‐helper‐cell subtype‐specific enhancers

Transcription factors (TFs) regulate cell‐type‐specific gene expression programs by combinatorial binding to cis‐genomic elements, particularly enhancers, subsequently leading to the recruitment of cofactors, and the general transcriptional machinery to target genes. Using data integration of genome...

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Veröffentlicht in:	European journal of immunology 2015-11, Vol.45 (11), p.3150-3157
Hauptverfasser:	Fang, Zhuo, Hecklau, Katharina, Gross, Fridolin, Bachmann, Ivo, Venzke, Melanie, Karl, Martin, Schuchhardt, Johannes, Radbruch, Andreas, Herzel, Hanspeter, Baumgrass, Ria
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Chromatin Immunoprecipitation Enhancer • Meta‐analysis • STAT • Th‐cell • Transcription factor Gene expression Gene Expression Regulation - genetics Gene Expression Regulation - immunology Genomes Mice Molecular Sequence Data T-Lymphocyte Subsets - immunology T-Lymphocytes, Helper-Inducer - immunology Transcription Factors - immunology
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