A possible role for nerve growth factor in the augmentation of sodium channels in models of chronic pain

Inflammation induces an upregulation of sodium channels in sensory neurons. This most likely occurs as a result of the retrograde transport of cytochemical mediators released during the inflammatory response. The purpose of this study was to determine the effect of the subcutaneous administration of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 2000-01, Vol.854 (1), p.19-29
Hauptverfasser:	Gould, Harry J., Gould, Trevor N., England, John D., Paul, Dennis, Liu, Z.P., Levinson, S.Rock
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - pharmacology Behavior, Animal - drug effects Biological and medical sciences Chronic Disease Ganglia, Spinal - metabolism Ganglia, Spinal - pathology Hindlimb Hot Temperature Hyperalgesia Hyperalgesia - chemically induced Hyperalgesia - physiopathology Inflammatory pain Medical sciences Nerve growth factor Nerve Growth Factor - immunology Nerve Growth Factor - pharmacology Nerve Growth Factor - physiology Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Neurons - metabolism Pain - metabolism Rats Rats, Sprague-Dawley Reaction Time - drug effects Sodium channel Sodium Channels - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!