Single nucleotide polymorphism of toll-like receptor 4 (TLR4) is associated with juvenile spondyloarthritis in Croatian population

Single nucleotide polymorphisms (SNP) of toll-like and NOD-like receptors have been associated with altered receptor activity and modified production of proinflammatory cytokines leading to a number of diseases. Our aim was to determine whether SNP of TLR2 (Arg753Gln), TLR4 (Asp299Gly, Thr399Ile), a...

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Veröffentlicht in:	Clinical rheumatology 2015-12, Vol.34 (12), p.2079-2086
Hauptverfasser:	Perica, Marija, Vidović, Mandica, Lamot, Lovro, Bukovac, Lana Tambić, Kapitanović, Sanja, Perić, Magdalena, Barbić, Jerko, Harjaček, Miroslav
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Arthritis, Juvenile - genetics Carrier Proteins - genetics Case-Control Studies Child Croatia European Continental Ancestry Group - genetics Female Gene Frequency Genetic Predisposition to Disease Genotype Heterozygote Humans Male Medicine Medicine & Public Health Middle Aged NLR Family, Pyrin Domain-Containing 3 Protein Original Article Polymorphism, Single Nucleotide Real-Time Polymerase Chain Reaction Rheumatology Spondylarthropathies - genetics Toll-Like Receptor 2 - genetics Toll-Like Receptor 4 - genetics Young Adult
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