Oral Targeted Therapies and Central Nervous System (CNS) Metastases

The purpose of our review is to summarize the clinical activity of oral targeted agents against brain metastases. This includes BRAF inhibitors (dabrafenib and vemurafenib), human epidermal growth factor receptor inhibitors (lapatinib, gefitinib, erlotinib, and afatinib), multi-kinase angiogenesis i...

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Veröffentlicht in:	CNS drugs 2015-11, Vol.29 (11), p.935-952
Hauptverfasser:	Gabay, Michael P., Wirth, Scott M., Stachnik, Joan M., Overley, Colleen L., Long, Katie E., Bressler, Linda R., Villano, John L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Antineoplastic Agents - administration & dosage Brain Neoplasms - drug therapy Brain Neoplasms - secondary Chemotherapy Clinical trials Confidence intervals Drug dosages Humans Medicine Medicine & Public Health Melanoma Metastasis Mutation Nervous system Neurology Neurosciences Ovarian cancer Patients Pharmacotherapy Psychiatry Psychopharmacology Response rates Review Article Studies Toxicity
Online-Zugang:	Volltext
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