Reactive Oxygen Species in Cancer: A Dance with the Devil
Reactive oxygen species (ROS) can initiate cancer, but oxidant generation in tumors leaves them vulnerable to further stresses. In this issue of Cancer Cell, Harris and colleagues show that augmenting oxidant stress in normal cells limits tumor initiation and progression. Hence, strategic targeting...
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| Veröffentlicht in: | Cancer cell 2015-02, Vol.27 (2), p.156-157 |
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| container_title | Cancer cell |
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| creator | Schumacker, Paul T. |
| description | Reactive oxygen species (ROS) can initiate cancer, but oxidant generation in tumors leaves them vulnerable to further stresses. In this issue of Cancer Cell, Harris and colleagues show that augmenting oxidant stress in normal cells limits tumor initiation and progression. Hence, strategic targeting of antioxidant systems may undermine survival of new tumor cells.
Reactive oxygen species (ROS) can initiate cancer, but oxidant generation in tumors leaves them vulnerable to further stresses. In this issue of Cancer Cell, Harris and colleagues show that augmenting oxidant stress in normal cells limits tumor initiation and progression. Hence, strategic targeting of antioxidant systems may undermine survival of new tumor cells. |
| doi_str_mv | 10.1016/j.ccell.2015.01.007 |
| format | Article |
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| ispartof | Cancer cell, 2015-02, Vol.27 (2), p.156-157 |
| issn | 1535-6108 1878-3686 |
| language | eng |
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| source | MEDLINE; Cell Press Archives; Elsevier ScienceDirect Journals Complete; EZB Electronic Journals Library |
| subjects | Animals Antioxidants - metabolism Breast Neoplasms - genetics Female Glutamate-Cysteine Ligase - genetics Humans Mammary Neoplasms, Animal - genetics |
| title | Reactive Oxygen Species in Cancer: A Dance with the Devil |
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