Knocking down schistosomes – promise for lentiviral transduction in parasites
Highlights • We review some key applications of RNAi to Schistosoma mansoni. • We appraise delivery systems for transgenesis and stable gene silencing. • We discuss prospects of lentiviral transduction for functional genomic explorations of parasites.
Gespeichert in:
| Veröffentlicht in: | Trends in parasitology 2015-07, Vol.31 (7), p.324-332 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 332 |
|---|---|
| container_issue | 7 |
| container_start_page | 324 |
| container_title | Trends in parasitology |
| container_volume | 31 |
| creator | Hagen, Jana Scheerlinck, Jean-Pierre Y Gasser, Robin B |
| description | Highlights • We review some key applications of RNAi to Schistosoma mansoni. • We appraise delivery systems for transgenesis and stable gene silencing. • We discuss prospects of lentiviral transduction for functional genomic explorations of parasites. |
| doi_str_mv | 10.1016/j.pt.2015.03.009 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1751202818</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1471492215000628</els_id><sourcerecordid>1694704771</sourcerecordid><originalsourceid>FETCH-LOGICAL-c438t-a83debaf800bb58c938f04b271c45ab0dd22f2e4b8b7a66582ee5625ccc5cfbf3</originalsourceid><addsrcrecordid>eNqFkr2O1DAURi0EYn-gp0IpaSZc23HsUCChFSyIlbYAast2bsCzGTvYzqLteAfekCfBoxkoKKCyi_N9ujr3EvKEQkuB9s-37VJaBlS0wFuA4R45pZ2kGwEg7x__3cDYCTnLeQsVlHJ4SE6YGDgfWH9Krt-H6G58-NyM8Vtosvvic4k57jA3P7__aJYUdz5jM8XUzBiKv_XJzE1JJuRxdcXH0PjQLCaZ7AvmR-TBZOaMj4_vOfn05vXHi7ebq-vLdxevrjau46psjOIjWjMpAGuFcgNXE3SWSeo6YSyMI2MTw84qK03fC8UQRc-Ec064yU78nDw79NYBv66Yi65jOpxnEzCuWVMpKAOmqPo_2g-dhE5KWlE4oC7FnBNOekl-Z9KdpqD3xvVWL0XvjWvguhqvkafH9tXucPwT-K24Ai8OAFYdtx6Tzs5jcDj6hK7oMfp_tb_8K-xmH7wz8w3eYd7GNYWqWVOdmQb9Yb_x_cJpvQDomeK_AIQsp0c</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1694704771</pqid></control><display><type>article</type><title>Knocking down schistosomes – promise for lentiviral transduction in parasites</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Hagen, Jana ; Scheerlinck, Jean-Pierre Y ; Gasser, Robin B</creator><creatorcontrib>Hagen, Jana ; Scheerlinck, Jean-Pierre Y ; Gasser, Robin B</creatorcontrib><description>Highlights • We review some key applications of RNAi to Schistosoma mansoni. • We appraise delivery systems for transgenesis and stable gene silencing. • We discuss prospects of lentiviral transduction for functional genomic explorations of parasites.</description><identifier>ISSN: 1471-4922</identifier><identifier>EISSN: 1471-5007</identifier><identifier>DOI: 10.1016/j.pt.2015.03.009</identifier><identifier>PMID: 25933926</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Gastroenterology and Hepatology ; helminth ; Infectious Disease ; Lentivirus ; Lentivirus - genetics ; microRNA ; RNA Interference ; RNA, Double-Stranded - genetics ; Schistosoma ; Schistosoma mansoni ; Schistosoma mansoni - genetics ; Schistosoma mansoni - pathogenicity ; Schistosomiasis - prevention & control ; short interfering RNA ; Trematoda</subject><ispartof>Trends in parasitology, 2015-07, Vol.31 (7), p.324-332</ispartof><rights>Elsevier Ltd</rights><rights>2015 Elsevier Ltd</rights><rights>Copyright © 2015 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c438t-a83debaf800bb58c938f04b271c45ab0dd22f2e4b8b7a66582ee5625ccc5cfbf3</citedby><cites>FETCH-LOGICAL-c438t-a83debaf800bb58c938f04b271c45ab0dd22f2e4b8b7a66582ee5625ccc5cfbf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.pt.2015.03.009$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25933926$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hagen, Jana</creatorcontrib><creatorcontrib>Scheerlinck, Jean-Pierre Y</creatorcontrib><creatorcontrib>Gasser, Robin B</creatorcontrib><title>Knocking down schistosomes – promise for lentiviral transduction in parasites</title><title>Trends in parasitology</title><addtitle>Trends Parasitol</addtitle><description>Highlights • We review some key applications of RNAi to Schistosoma mansoni. • We appraise delivery systems for transgenesis and stable gene silencing. • We discuss prospects of lentiviral transduction for functional genomic explorations of parasites.</description><subject>Animals</subject><subject>Gastroenterology and Hepatology</subject><subject>helminth</subject><subject>Infectious Disease</subject><subject>Lentivirus</subject><subject>Lentivirus - genetics</subject><subject>microRNA</subject><subject>RNA Interference</subject><subject>RNA, Double-Stranded - genetics</subject><subject>Schistosoma</subject><subject>Schistosoma mansoni</subject><subject>Schistosoma mansoni - genetics</subject><subject>Schistosoma mansoni - pathogenicity</subject><subject>Schistosomiasis - prevention & control</subject><subject>short interfering RNA</subject><subject>Trematoda</subject><issn>1471-4922</issn><issn>1471-5007</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkr2O1DAURi0EYn-gp0IpaSZc23HsUCChFSyIlbYAast2bsCzGTvYzqLteAfekCfBoxkoKKCyi_N9ujr3EvKEQkuB9s-37VJaBlS0wFuA4R45pZ2kGwEg7x__3cDYCTnLeQsVlHJ4SE6YGDgfWH9Krt-H6G58-NyM8Vtosvvic4k57jA3P7__aJYUdz5jM8XUzBiKv_XJzE1JJuRxdcXH0PjQLCaZ7AvmR-TBZOaMj4_vOfn05vXHi7ebq-vLdxevrjau46psjOIjWjMpAGuFcgNXE3SWSeo6YSyMI2MTw84qK03fC8UQRc-Ec064yU78nDw79NYBv66Yi65jOpxnEzCuWVMpKAOmqPo_2g-dhE5KWlE4oC7FnBNOekl-Z9KdpqD3xvVWL0XvjWvguhqvkafH9tXucPwT-K24Ai8OAFYdtx6Tzs5jcDj6hK7oMfp_tb_8K-xmH7wz8w3eYd7GNYWqWVOdmQb9Yb_x_cJpvQDomeK_AIQsp0c</recordid><startdate>20150701</startdate><enddate>20150701</enddate><creator>Hagen, Jana</creator><creator>Scheerlinck, Jean-Pierre Y</creator><creator>Gasser, Robin B</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7U9</scope><scope>H94</scope><scope>M7N</scope></search><sort><creationdate>20150701</creationdate><title>Knocking down schistosomes – promise for lentiviral transduction in parasites</title><author>Hagen, Jana ; Scheerlinck, Jean-Pierre Y ; Gasser, Robin B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-a83debaf800bb58c938f04b271c45ab0dd22f2e4b8b7a66582ee5625ccc5cfbf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Animals</topic><topic>Gastroenterology and Hepatology</topic><topic>helminth</topic><topic>Infectious Disease</topic><topic>Lentivirus</topic><topic>Lentivirus - genetics</topic><topic>microRNA</topic><topic>RNA Interference</topic><topic>RNA, Double-Stranded - genetics</topic><topic>Schistosoma</topic><topic>Schistosoma mansoni</topic><topic>Schistosoma mansoni - genetics</topic><topic>Schistosoma mansoni - pathogenicity</topic><topic>Schistosomiasis - prevention & control</topic><topic>short interfering RNA</topic><topic>Trematoda</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hagen, Jana</creatorcontrib><creatorcontrib>Scheerlinck, Jean-Pierre Y</creatorcontrib><creatorcontrib>Gasser, Robin B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><jtitle>Trends in parasitology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hagen, Jana</au><au>Scheerlinck, Jean-Pierre Y</au><au>Gasser, Robin B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Knocking down schistosomes – promise for lentiviral transduction in parasites</atitle><jtitle>Trends in parasitology</jtitle><addtitle>Trends Parasitol</addtitle><date>2015-07-01</date><risdate>2015</risdate><volume>31</volume><issue>7</issue><spage>324</spage><epage>332</epage><pages>324-332</pages><issn>1471-4922</issn><eissn>1471-5007</eissn><abstract>Highlights • We review some key applications of RNAi to Schistosoma mansoni. • We appraise delivery systems for transgenesis and stable gene silencing. • We discuss prospects of lentiviral transduction for functional genomic explorations of parasites.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>25933926</pmid><doi>10.1016/j.pt.2015.03.009</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1471-4922 |
| ispartof | Trends in parasitology, 2015-07, Vol.31 (7), p.324-332 |
| issn | 1471-4922 1471-5007 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1751202818 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Gastroenterology and Hepatology helminth Infectious Disease Lentivirus Lentivirus - genetics microRNA RNA Interference RNA, Double-Stranded - genetics Schistosoma Schistosoma mansoni Schistosoma mansoni - genetics Schistosoma mansoni - pathogenicity Schistosomiasis - prevention & control short interfering RNA Trematoda |
| title | Knocking down schistosomes – promise for lentiviral transduction in parasites |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T13%3A46%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Knocking%20down%20schistosomes%20%E2%80%93%20promise%20for%20lentiviral%20transduction%20in%20parasites&rft.jtitle=Trends%20in%20parasitology&rft.au=Hagen,%20Jana&rft.date=2015-07-01&rft.volume=31&rft.issue=7&rft.spage=324&rft.epage=332&rft.pages=324-332&rft.issn=1471-4922&rft.eissn=1471-5007&rft_id=info:doi/10.1016/j.pt.2015.03.009&rft_dat=%3Cproquest_cross%3E1694704771%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1694704771&rft_id=info:pmid/25933926&rft_els_id=S1471492215000628&rfr_iscdi=true |