Rolling the Dice to Discover the Role of DICER in Tumorigenesis
In an effort to identify the consequences of complete DICER1 loss in tumorigenesis, in this issue of Cancer Cell, Ravi et al. characterize the effects of homozygous deletion of Dicer1. Using an in vivo mouse model, they show that genetic deletion of Dicer1 does not preclude tumor formation.
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| Veröffentlicht in: | Cancer cell 2012-06, Vol.21 (6), p.717-719 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | In an effort to identify the consequences of complete DICER1 loss in tumorigenesis, in this issue of Cancer Cell, Ravi et al. characterize the effects of homozygous deletion of Dicer1. Using an in vivo mouse model, they show that genetic deletion of Dicer1 does not preclude tumor formation. |
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| ISSN: | 1535-6108 1878-3686 |
| DOI: | 10.1016/j.ccr.2012.05.030 |