Positively and negatively surface-charged chondroitin sulfate-trimethylchitosan nanoparticles as protein carriers

•We developed a novel nanoparticular carrier system via polyelectrolyte complexation.•Nanoparticles (NPs) with positive and negative surface charge were prepared.•NPs are prepared in aqueous under extremely mild conditions and in a very short time.•Both charged NPs show cytocompatibility and were ph...

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Veröffentlicht in:	Carbohydrate polymers 2016-02, Vol.137, p.532-540
Hauptverfasser:	Young, Jenn-jong, Chen, Cheng-cheung, Chen, Ying-chuan, Cheng, Kuang-ming, Yen, Hui-Ju, Huang, Yu-chuan, Tsai, Tsung-Neng
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Cell Survival - drug effects Cell uptake Chitosan - analogs & derivatives Chondroitin sulfate Chondroitin Sulfates - chemistry Cytotoxicity Human Umbilical Vein Endothelial Cells Humans Nanocapsules - adverse effects Nanocapsules - chemistry Nanoparticles Static Electricity Trimethylchitosan Zeta potential
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