Identification and Initial Characterization of Four Novel Members of the Interleukin-1 Family

Interleukin-1 (IL-1), fibroblast growth factors (FGFs), and their homologues are secreted factors that share a common β-barrel structure and act on target cells by binding to cell surface receptors with immunoglobulin-like folds in their extracellular domain. While numerous members of the FGF family...

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Veröffentlicht in:	The Journal of biological chemistry 2000-04, Vol.275 (14), p.10308-10314
Hauptverfasser:	Kumar, Sanjay, McDonnell, Peter C., Lehr, Ruth, Tierney, Lauren, Tzimas, Maritsa N., Griswold, Don E., Capper, Elizabeth A., Tal-Singer, Ruth, Wells, Grace I., Doyle, Michael L., Young, Peter R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cells, Cultured Circular Dichroism Cloning, Molecular Epithelium - immunology fibroblast growth factor Gene Expression Regulation - drug effects Herpes Simplex - immunology Herpes simplex virus Herpesvirus 1, Human Humans interleukin 1 receptors Interleukin-1 - biosynthesis Interleukin-1 - chemistry Interleukin-1 - genetics Keratinocytes - drug effects Keratinocytes - immunology Mice Molecular Sequence Data Oxazolone - pharmacology Protein Folding Protein Isoforms - biosynthesis Protein Isoforms - chemistry Protein Isoforms - genetics Protein Structure, Secondary Recombinant Proteins - chemistry Recombinant Proteins - metabolism RNA, Messenger - genetics Sequence Alignment Sequence Homology, Amino Acid
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