γδ T Cells Shape Preimmune Peripheral B Cell Populations

We previously reported that selective ablation of certain γδ T cell subsets, rather than removal of all γδ T cells, strongly affects serum Ab levels in nonimmunized mice. This type of manipulation also changed T cells, including residual γδ T cells, revealing some interdependence of γδ T cell popula...

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Veröffentlicht in:	The Journal of immunology (1950) 2016-01, Vol.196 (1), p.217-231
Hauptverfasser:	Huang, Yafei, Getahun, Andrew, Heiser, Ryan A, Detanico, Thiago O, Aviszus, Katja, Kirchenbaum, Greg A, Casper, Tamara L, Huang, Chunjian, Aydintug, M Kemal, Carding, Simon R, Ikuta, Koichi, Huang, Hua, Wysocki, Lawrence J, Cambier, John C, O'Brien, Rebecca L, Born, Willi K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals Antibodies - blood Autoantibodies - blood B-Cell Activating Factor - blood B-Lymphocytes - immunology Cells, Cultured Coculture Techniques Germinal Center - immunology Immunoglobulin G - blood Interleukin-4 - biosynthesis Interleukin-4 - blood Mice Mice, Inbred C57BL Mice, Knockout Receptors, Antigen, T-Cell, gamma-delta - genetics Receptors, Antigen, T-Cell, gamma-delta - immunology Spleen - cytology Spleen - immunology T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - transplantation
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