Ultraviolet Damage and Nucleosome Folding of the 5S Ribosomal RNA Gene

The Xenopus borealis somatic 5S ribosomal RNA gene was used as a model system to determine the mutual effects of nucleosome folding and formation of ultraviolet (UV) photoproducts (primarily cis−syn cyclobutane pyrimidine dimers, or CPDs) in chromatin. We analyzed the preferred rotational and transl...

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Veröffentlicht in:	Biochemistry 2000-01, Vol.39 (3), p.557-566
Hauptverfasser:	Liu, Xiaoqi, Mann, David B, Suquet, Christine, Springer, David L, Smerdon, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BASIC BIOLOGICAL SCIENCES CHROMATIN Chromatin - radiation effects cyclobutane pyrimidine dimers DIGESTION DISTRIBUTION DNA DNA, Ribosomal - genetics DNA, Ribosomal - radiation effects DNA-Directed DNA Polymerase Dose-Response Relationship, Radiation ENZYMES GENES HISTONES Histones - metabolism Histones - radiation effects Hydroxyl Radical - analysis HYDROXYL RADICALS INDUCTION MODULATION NUCLEASES NUCLEOSOMES Nucleosomes - genetics Nucleosomes - radiation effects PYRIMIDINE DIMERS PYRIMIDINES RIBOSOMAL RNA RNA, Ribosomal, 5S - genetics RNA, Ribosomal, 5S - radiation effects rRNA 5S Ultraviolet Rays Viral Proteins - metabolism Xenopus Xenopus borealis
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