The role of additives in moderating the influence of Fe(III) and Cu(II) on the radiochemical yield of [68Ga(DOTATATE)]

[68Ga(DOTATATE)] has demonstrated its clinical usefulness. Both Fe3+ and Cu2+, potential contaminants in Gallium-68 generator eluent, substantially reduce the radiochemical (RC) yield of [68Ga(DOTATATE)] if the metal/ligand ratio of 1:1 is exceeded. A variety of compounds were examined for their pot...

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Veröffentlicht in:	Applied radiation and isotopes 2016-01, Vol.107, p.13-16
Hauptverfasser:	Oehlke, Elisabeth, Lengkeek, Nigel A., So Le, Van, Pellegrini, Paul A., Greguric, Ivan, Weiner, Ron
Format:	Artikel
Sprache:	eng
Schlagworte:	68Ga radiolabelling Additives Ascorbic acid DOTATATE Metal ion contamination PET Phosphate
Online-Zugang:	Volltext
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