Primary and secondary alterations of white matter connectivity in schizophrenia: A study on first-episode and chronic patients using whole-brain tractography-based analysis

AbstractSchizophrenia is a debilitating mental disorder that is associated with an impaired connection of cerebral white matter. Studies on patients with chronic and first-episode schizophrenia have found widespread white matter abnormalities. However, it is unclear whether the altered connections a...

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Veröffentlicht in:	Schizophrenia research 2015-12, Vol.169 (1), p.54-61
Hauptverfasser:	Wu, Chen-Hao, Hwang, Tzung-Jeng, Chen, Yu-Jen, Hsu, Yung-Chin, Lo, Yu-Chun, Liu, Chih-Min, Hwu, Hai-Gwo, Liu, Chen-Chung, Hsieh, Ming H, Chien, Yi-Ling, Chen, Chung-Ming, Isaac Tseng, Wen-Yih
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Brain - pathology Chronic Disease Cohort Studies Diffusion Magnetic Resonance Imaging Diffusion spectrum imaging Disease Progression Female First-episode Humans Imaging, Three-Dimensional Male Neural Pathways - pathology Pattern Recognition, Automated Psychiatric Status Rating Scales Psychiatric/Mental Health Regression Analysis Schizophrenia Schizophrenia - pathology Tractography White Matter - pathology White matter connectivity
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