Miniaturized Cultivation of Microbiota for Antimalarial Drug Discovery

The ongoing search for effective antiplasmodial agents remains essential in the fight against malaria worldwide. Emerging parasitic drug resistance places an urgent need to explore chemotherapies with novel structures and mechanisms of action. Natural products have historically provided effective an...

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Veröffentlicht in:	Medicinal research reviews 2016-01, Vol.36 (1), p.144-168
Hauptverfasser:	Waterman, Carrie, Calcul, Laurent, Beau, Jeremy, Ma, Wai Sheung, Lebar, Matthew D., von Salm, Jacqueline L., Harter, Charles, Mutka, Tina, Morton, Lindsay C., Maignan, Patrick, Barisic, Betty, van Olphen, Alberto, Kyle, Dennis E., Vrijmoed, Lilian, Pang, Ka-Lai, Pearce, Cedric J., Baker, Bill J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimalarials - isolation & purification Bacteria - growth & development Bacteriological Techniques - methods Biological Assay Cell Line, Tumor Cercopithecus aethiops Chromatography Dogs Drug Discovery Drug Resistance endophytes Fungi - growth & development high-throughput screening Humans Inhibitory Concentration 50 Invertebrates - microbiology Madin Darby Canine Kidney Cells Magnetic Resonance Spectroscopy Malaria Malaria - drug therapy microbe cultivation Microbiota Miniaturization Mycology - methods natural products Pharmaceutical industry Plant Extracts - chemistry Plasmodium falciparum - drug effects Vero Cells
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