Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis

15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) induces reactive oxygen species (ROS)-mediated apoptosis in many malignant cells, which has not been studied in hepatoma cells. In this study, we investigated whether 15d-PGJ2 induced apoptosis in hepatocellular carcinoma (HCC) associated with ROS. The LM3...

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Veröffentlicht in:OncoTargets and therapy 2015, Vol.8, p.3585-3593
Hauptverfasser: Chen, Kan, Dai, Weiqi, Wang, Fan, Xia, Yujing, Li, Jingjing, Li, Sainan, Liu, Tong, Zhang, Rong, Wang, Jianrong, Lu, Wenxia, Zhou, Yuqing, Yin, Qin, Zheng, Yuanyuan, Abudumijiti, Huerxidan, Chen, Rongxia, Lu, Jie, Zhou, Yingqun, Guo, Chuanyong
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Sprache:eng
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