Oxidation and Cognitive Impairment in the Aging Zebrafish

Background: The zebrafish has become an established model organism in aging research giving insight into general aging processes in vertebrates. Oxidative stress in aging may damage proteins and lipids in brain cells. Enhanced levels of oxidized macromolecules exert neurotoxic effects that could lea...

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Veröffentlicht in:	Gerontology (Basel) 2015-12, Vol.62 (1), p.47-57
Hauptverfasser:	Ruhl, Tim, Jonas, Annika, Seidel, Nathan Ian, Prinz, Nicole, Albayram, Onder, Bilkei-Gorzo, Andras, von der Emde, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - physiology Analysis Animals Association Learning - physiology Associative learning Cognition & reasoning Cognition Disorders - physiopathology Danio rerio Discrimination Learning - physiology Experimental Section / Original Paper Geriatric cognitive disorders Gerontology Learning - physiology Lipid Peroxidation Lipofuscin - metabolism Oxidation-reduction reactions Oxidative stress Oxidative Stress - physiology Physiological aspects Protein Carbonylation Risk factors Spatial Learning - physiology Telencephalon - metabolism Thiobarbituric Acid Reactive Substances - metabolism Zebrafish
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