Endurance Exercise-Induced Cardiac Remodeling: Not All Sports Are Created Equal
Background The term endurance sport (ES) is broadly used to characterize any exercise that requires maintenance of high cardiac output over extended time. However, the relative amount of isotonic (volume) versus isometric (pressure) cardiac stress varies across ES disciplines. To what degree ES-medi...
Gespeichert in:
| Veröffentlicht in: | Journal of the American Society of Echocardiography 2015-12, Vol.28 (12), p.1434-1440 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1440 |
|---|---|
| container_issue | 12 |
| container_start_page | 1434 |
| container_title | Journal of the American Society of Echocardiography |
| container_volume | 28 |
| creator | Wasfy, Meagan M., MD Weiner, Rory B., MD Wang, Francis, MD Berkstresser, Brant, MS, ATC Lewis, Gregory D., MD DeLuca, James R., BA Hutter, Adolph M., MD Picard, Michael H., MD Baggish, Aaron L., MD |
| description | Background The term endurance sport (ES) is broadly used to characterize any exercise that requires maintenance of high cardiac output over extended time. However, the relative amount of isotonic (volume) versus isometric (pressure) cardiac stress varies across ES disciplines. To what degree ES-mediated cardiac remodeling varies, as a function of superimposed isometric stress, is uncertain. The aim of this study was to compare the cardiac remodeling characteristics associated with two common yet physiologically distinct forms of ES. Methods Healthy competitive male long-distance runners (high isotonic, low isometric stress; n = 40) and rowers (high isotonic, high isometric stress; n = 40) were comparatively studied after 3 months of sport-specific exercise training with conventional and speckle-tracking two-dimensional echocardiography. Results Rowers demonstrated dilated left ventricular (LV) volumes and elevated LV mass (i.e., eccentric LV hypertrophy), whereas runners demonstrated normal LV mass (runners, 88 ± 11 g/m2 ; rowers, 108 ± 13 g/m2 ; P |
| doi_str_mv | 10.1016/j.echo.2015.08.002 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1749616476</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0894731715005933</els_id><sourcerecordid>1749616476</sourcerecordid><originalsourceid>FETCH-LOGICAL-c481t-4c5ff061dd9856108b80a21b9979e648f2e832b3f9a336ecf8be3c310c1034143</originalsourceid><addsrcrecordid>eNp9kcFu1DAURS0EokPLD7BAWbJJ-l6cODZCSKPRQCtVVGphbTnOC3jIxFM7Qe3f42gKiy66svR07pV8LmPvEAoEFOe7guwvX5SAdQGyAChfsBWCanLRqPolW4FUVd5wbE7Ymxh3AFBLgNfspBRcoKxxxa63YzcHM1rKtvcUrIuUX6aTpS7bmNA5Y7Mb2vuOBjf-_Jh981O2Hobs9uDDFLN1oGwTyEwJ397NZjhjr3ozRHr7-J6yH1-23zcX-dX118vN-iq3lcQpr2zd9yCw65SsBYJsJZgSW6UaRaKSfUmSly3vleFckO1lS9xyBIvAK6z4Kftw7D0EfzdTnPTeRUvDYEbyc9TYVEqgqBqR0PKI2uBjDNTrQ3B7Ex40gl5E6p1eROpFpAapk8gUev_YP7d76v5H_plLwKcjQOmXfxwFHa2j5LFzgeykO--e7__8JG6TYGfN8JseKO78HMbkT6OOpQZ9u0y5LIl1GlFxzv8C0IKXIg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1749616476</pqid></control><display><type>article</type><title>Endurance Exercise-Induced Cardiac Remodeling: Not All Sports Are Created Equal</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Wasfy, Meagan M., MD ; Weiner, Rory B., MD ; Wang, Francis, MD ; Berkstresser, Brant, MS, ATC ; Lewis, Gregory D., MD ; DeLuca, James R., BA ; Hutter, Adolph M., MD ; Picard, Michael H., MD ; Baggish, Aaron L., MD</creator><creatorcontrib>Wasfy, Meagan M., MD ; Weiner, Rory B., MD ; Wang, Francis, MD ; Berkstresser, Brant, MS, ATC ; Lewis, Gregory D., MD ; DeLuca, James R., BA ; Hutter, Adolph M., MD ; Picard, Michael H., MD ; Baggish, Aaron L., MD</creatorcontrib><description>Background The term endurance sport (ES) is broadly used to characterize any exercise that requires maintenance of high cardiac output over extended time. However, the relative amount of isotonic (volume) versus isometric (pressure) cardiac stress varies across ES disciplines. To what degree ES-mediated cardiac remodeling varies, as a function of superimposed isometric stress, is uncertain. The aim of this study was to compare the cardiac remodeling characteristics associated with two common yet physiologically distinct forms of ES. Methods Healthy competitive male long-distance runners (high isotonic, low isometric stress; n = 40) and rowers (high isotonic, high isometric stress; n = 40) were comparatively studied after 3 months of sport-specific exercise training with conventional and speckle-tracking two-dimensional echocardiography. Results Rowers demonstrated dilated left ventricular (LV) volumes and elevated LV mass (i.e., eccentric LV hypertrophy), whereas runners demonstrated normal LV mass (runners, 88 ± 11 g/m2 ; rowers, 108 ± 13 g/m2 ; P < .001) despite comparatively larger LV volumes (runners, 101 ± 10 mL/m2 ; rowers, 89 ± 13 mL/m2 ; P < .001) consistent with eccentric LV remodeling. Increasing LV mass was associated with increased reliance on early diastolic filling (LV mass vs E′/A′ ratio, R = 0.47, P < .001) indicating “mass-dependent” diastolic function. Right ventricular dilation of similar magnitude and LV systolic function, as assessed by numerous complementary indices, were similar in both groups. Conclusions Cardiac adaptations differ significantly as a function of ES discipline. Further work is required to determine the mechanisms for this differential adaptation, to develop definitive ES discipline-specific normative values, and to evaluate the optimal therapeutic use of specific ES disciplines among patients with common cardiovascular diseases.</description><identifier>ISSN: 0894-7317</identifier><identifier>EISSN: 1097-6795</identifier><identifier>DOI: 10.1016/j.echo.2015.08.002</identifier><identifier>PMID: 26361851</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Cardiac remodeling ; Cardiovascular ; Cross-Sectional Studies ; Diastolic function ; Echocardiography, Doppler ; Endurance exercise ; Heart Ventricles - diagnostic imaging ; Heart Ventricles - physiopathology ; Humans ; Hypertrophy, Left Ventricular - diagnostic imaging ; Hypertrophy, Left Ventricular - physiopathology ; Left ventricular hypertrophy ; Male ; Myocardial Contraction - physiology ; Physical Endurance - physiology ; Running - physiology ; Ventricular Function, Left - physiology ; Ventricular Remodeling</subject><ispartof>Journal of the American Society of Echocardiography, 2015-12, Vol.28 (12), p.1434-1440</ispartof><rights>American Society of Echocardiography</rights><rights>2015 American Society of Echocardiography</rights><rights>Copyright © 2015 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-4c5ff061dd9856108b80a21b9979e648f2e832b3f9a336ecf8be3c310c1034143</citedby><cites>FETCH-LOGICAL-c481t-4c5ff061dd9856108b80a21b9979e648f2e832b3f9a336ecf8be3c310c1034143</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0894731715005933$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26361851$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wasfy, Meagan M., MD</creatorcontrib><creatorcontrib>Weiner, Rory B., MD</creatorcontrib><creatorcontrib>Wang, Francis, MD</creatorcontrib><creatorcontrib>Berkstresser, Brant, MS, ATC</creatorcontrib><creatorcontrib>Lewis, Gregory D., MD</creatorcontrib><creatorcontrib>DeLuca, James R., BA</creatorcontrib><creatorcontrib>Hutter, Adolph M., MD</creatorcontrib><creatorcontrib>Picard, Michael H., MD</creatorcontrib><creatorcontrib>Baggish, Aaron L., MD</creatorcontrib><title>Endurance Exercise-Induced Cardiac Remodeling: Not All Sports Are Created Equal</title><title>Journal of the American Society of Echocardiography</title><addtitle>J Am Soc Echocardiogr</addtitle><description>Background The term endurance sport (ES) is broadly used to characterize any exercise that requires maintenance of high cardiac output over extended time. However, the relative amount of isotonic (volume) versus isometric (pressure) cardiac stress varies across ES disciplines. To what degree ES-mediated cardiac remodeling varies, as a function of superimposed isometric stress, is uncertain. The aim of this study was to compare the cardiac remodeling characteristics associated with two common yet physiologically distinct forms of ES. Methods Healthy competitive male long-distance runners (high isotonic, low isometric stress; n = 40) and rowers (high isotonic, high isometric stress; n = 40) were comparatively studied after 3 months of sport-specific exercise training with conventional and speckle-tracking two-dimensional echocardiography. Results Rowers demonstrated dilated left ventricular (LV) volumes and elevated LV mass (i.e., eccentric LV hypertrophy), whereas runners demonstrated normal LV mass (runners, 88 ± 11 g/m2 ; rowers, 108 ± 13 g/m2 ; P < .001) despite comparatively larger LV volumes (runners, 101 ± 10 mL/m2 ; rowers, 89 ± 13 mL/m2 ; P < .001) consistent with eccentric LV remodeling. Increasing LV mass was associated with increased reliance on early diastolic filling (LV mass vs E′/A′ ratio, R = 0.47, P < .001) indicating “mass-dependent” diastolic function. Right ventricular dilation of similar magnitude and LV systolic function, as assessed by numerous complementary indices, were similar in both groups. Conclusions Cardiac adaptations differ significantly as a function of ES discipline. Further work is required to determine the mechanisms for this differential adaptation, to develop definitive ES discipline-specific normative values, and to evaluate the optimal therapeutic use of specific ES disciplines among patients with common cardiovascular diseases.</description><subject>Adolescent</subject><subject>Cardiac remodeling</subject><subject>Cardiovascular</subject><subject>Cross-Sectional Studies</subject><subject>Diastolic function</subject><subject>Echocardiography, Doppler</subject><subject>Endurance exercise</subject><subject>Heart Ventricles - diagnostic imaging</subject><subject>Heart Ventricles - physiopathology</subject><subject>Humans</subject><subject>Hypertrophy, Left Ventricular - diagnostic imaging</subject><subject>Hypertrophy, Left Ventricular - physiopathology</subject><subject>Left ventricular hypertrophy</subject><subject>Male</subject><subject>Myocardial Contraction - physiology</subject><subject>Physical Endurance - physiology</subject><subject>Running - physiology</subject><subject>Ventricular Function, Left - physiology</subject><subject>Ventricular Remodeling</subject><issn>0894-7317</issn><issn>1097-6795</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kcFu1DAURS0EokPLD7BAWbJJ-l6cODZCSKPRQCtVVGphbTnOC3jIxFM7Qe3f42gKiy66svR07pV8LmPvEAoEFOe7guwvX5SAdQGyAChfsBWCanLRqPolW4FUVd5wbE7Ymxh3AFBLgNfspBRcoKxxxa63YzcHM1rKtvcUrIuUX6aTpS7bmNA5Y7Mb2vuOBjf-_Jh981O2Hobs9uDDFLN1oGwTyEwJ397NZjhjr3ozRHr7-J6yH1-23zcX-dX118vN-iq3lcQpr2zd9yCw65SsBYJsJZgSW6UaRaKSfUmSly3vleFckO1lS9xyBIvAK6z4Kftw7D0EfzdTnPTeRUvDYEbyc9TYVEqgqBqR0PKI2uBjDNTrQ3B7Ex40gl5E6p1eROpFpAapk8gUev_YP7d76v5H_plLwKcjQOmXfxwFHa2j5LFzgeykO--e7__8JG6TYGfN8JseKO78HMbkT6OOpQZ9u0y5LIl1GlFxzv8C0IKXIg</recordid><startdate>20151201</startdate><enddate>20151201</enddate><creator>Wasfy, Meagan M., MD</creator><creator>Weiner, Rory B., MD</creator><creator>Wang, Francis, MD</creator><creator>Berkstresser, Brant, MS, ATC</creator><creator>Lewis, Gregory D., MD</creator><creator>DeLuca, James R., BA</creator><creator>Hutter, Adolph M., MD</creator><creator>Picard, Michael H., MD</creator><creator>Baggish, Aaron L., MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20151201</creationdate><title>Endurance Exercise-Induced Cardiac Remodeling: Not All Sports Are Created Equal</title><author>Wasfy, Meagan M., MD ; Weiner, Rory B., MD ; Wang, Francis, MD ; Berkstresser, Brant, MS, ATC ; Lewis, Gregory D., MD ; DeLuca, James R., BA ; Hutter, Adolph M., MD ; Picard, Michael H., MD ; Baggish, Aaron L., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-4c5ff061dd9856108b80a21b9979e648f2e832b3f9a336ecf8be3c310c1034143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adolescent</topic><topic>Cardiac remodeling</topic><topic>Cardiovascular</topic><topic>Cross-Sectional Studies</topic><topic>Diastolic function</topic><topic>Echocardiography, Doppler</topic><topic>Endurance exercise</topic><topic>Heart Ventricles - diagnostic imaging</topic><topic>Heart Ventricles - physiopathology</topic><topic>Humans</topic><topic>Hypertrophy, Left Ventricular - diagnostic imaging</topic><topic>Hypertrophy, Left Ventricular - physiopathology</topic><topic>Left ventricular hypertrophy</topic><topic>Male</topic><topic>Myocardial Contraction - physiology</topic><topic>Physical Endurance - physiology</topic><topic>Running - physiology</topic><topic>Ventricular Function, Left - physiology</topic><topic>Ventricular Remodeling</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wasfy, Meagan M., MD</creatorcontrib><creatorcontrib>Weiner, Rory B., MD</creatorcontrib><creatorcontrib>Wang, Francis, MD</creatorcontrib><creatorcontrib>Berkstresser, Brant, MS, ATC</creatorcontrib><creatorcontrib>Lewis, Gregory D., MD</creatorcontrib><creatorcontrib>DeLuca, James R., BA</creatorcontrib><creatorcontrib>Hutter, Adolph M., MD</creatorcontrib><creatorcontrib>Picard, Michael H., MD</creatorcontrib><creatorcontrib>Baggish, Aaron L., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Society of Echocardiography</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wasfy, Meagan M., MD</au><au>Weiner, Rory B., MD</au><au>Wang, Francis, MD</au><au>Berkstresser, Brant, MS, ATC</au><au>Lewis, Gregory D., MD</au><au>DeLuca, James R., BA</au><au>Hutter, Adolph M., MD</au><au>Picard, Michael H., MD</au><au>Baggish, Aaron L., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endurance Exercise-Induced Cardiac Remodeling: Not All Sports Are Created Equal</atitle><jtitle>Journal of the American Society of Echocardiography</jtitle><addtitle>J Am Soc Echocardiogr</addtitle><date>2015-12-01</date><risdate>2015</risdate><volume>28</volume><issue>12</issue><spage>1434</spage><epage>1440</epage><pages>1434-1440</pages><issn>0894-7317</issn><eissn>1097-6795</eissn><abstract>Background The term endurance sport (ES) is broadly used to characterize any exercise that requires maintenance of high cardiac output over extended time. However, the relative amount of isotonic (volume) versus isometric (pressure) cardiac stress varies across ES disciplines. To what degree ES-mediated cardiac remodeling varies, as a function of superimposed isometric stress, is uncertain. The aim of this study was to compare the cardiac remodeling characteristics associated with two common yet physiologically distinct forms of ES. Methods Healthy competitive male long-distance runners (high isotonic, low isometric stress; n = 40) and rowers (high isotonic, high isometric stress; n = 40) were comparatively studied after 3 months of sport-specific exercise training with conventional and speckle-tracking two-dimensional echocardiography. Results Rowers demonstrated dilated left ventricular (LV) volumes and elevated LV mass (i.e., eccentric LV hypertrophy), whereas runners demonstrated normal LV mass (runners, 88 ± 11 g/m2 ; rowers, 108 ± 13 g/m2 ; P < .001) despite comparatively larger LV volumes (runners, 101 ± 10 mL/m2 ; rowers, 89 ± 13 mL/m2 ; P < .001) consistent with eccentric LV remodeling. Increasing LV mass was associated with increased reliance on early diastolic filling (LV mass vs E′/A′ ratio, R = 0.47, P < .001) indicating “mass-dependent” diastolic function. Right ventricular dilation of similar magnitude and LV systolic function, as assessed by numerous complementary indices, were similar in both groups. Conclusions Cardiac adaptations differ significantly as a function of ES discipline. Further work is required to determine the mechanisms for this differential adaptation, to develop definitive ES discipline-specific normative values, and to evaluate the optimal therapeutic use of specific ES disciplines among patients with common cardiovascular diseases.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26361851</pmid><doi>10.1016/j.echo.2015.08.002</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0894-7317 |
| ispartof | Journal of the American Society of Echocardiography, 2015-12, Vol.28 (12), p.1434-1440 |
| issn | 0894-7317 1097-6795 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1749616476 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Cardiac remodeling Cardiovascular Cross-Sectional Studies Diastolic function Echocardiography, Doppler Endurance exercise Heart Ventricles - diagnostic imaging Heart Ventricles - physiopathology Humans Hypertrophy, Left Ventricular - diagnostic imaging Hypertrophy, Left Ventricular - physiopathology Left ventricular hypertrophy Male Myocardial Contraction - physiology Physical Endurance - physiology Running - physiology Ventricular Function, Left - physiology Ventricular Remodeling |
| title | Endurance Exercise-Induced Cardiac Remodeling: Not All Sports Are Created Equal |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T00%3A48%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Endurance%20Exercise-Induced%20Cardiac%20Remodeling:%20Not%20All%20Sports%20Are%20Created%20Equal&rft.jtitle=Journal%20of%20the%20American%20Society%20of%20Echocardiography&rft.au=Wasfy,%20Meagan%20M.,%20MD&rft.date=2015-12-01&rft.volume=28&rft.issue=12&rft.spage=1434&rft.epage=1440&rft.pages=1434-1440&rft.issn=0894-7317&rft.eissn=1097-6795&rft_id=info:doi/10.1016/j.echo.2015.08.002&rft_dat=%3Cproquest_cross%3E1749616476%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1749616476&rft_id=info:pmid/26361851&rft_els_id=S0894731715005933&rfr_iscdi=true |