Fut3 role in breast invasive ductal carcinoma: Investigating its gene promoter and protein expression

Fucosylated glycans synthesized by α1,3/4-fucosyltransferase (FUT3) enzyme play an important role in breast cancer prognosis and metastasis, being involved in the binding of circulating tumor cells to the endothelium and being related to tumor stage, metastatic potential and chemoresistance. Despite...

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Veröffentlicht in:	Experimental and molecular pathology 2015-12, Vol.99 (3), p.409-415
Hauptverfasser:	Nascimento, Jessica Catarine Frutuoso do, Ferreira, Steffany de Almeida, Vasconcelos, Juliana Lúcia de Albuquerque, Silva-Filho, João Luiz Quirino da, Barbosa, Bruno Trajano, Bezerra, Matheus Filgueira, Rocha, Cíntia Renata Costa, Beltrão, Eduardo Isidoro Carneiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Brazil Breast Neoplasms - genetics Breast Neoplasms - pathology Carcinoma, Ductal, Breast - genetics Carcinoma, Ductal, Breast - pathology Female Fucosyltransferases - genetics Fucosyltransferases - metabolism FucT-III Gene Expression Regulation, Neoplastic - genetics Human mammary carcinoma Humans Immunohistochemistry - methods Lewis X Antigen - metabolism Promoter Regions, Genetic Protein expression Regulatory region Single nucleotide polymorphism
Online-Zugang:	Volltext
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