The relationship of miR-146a gene polymorphism with carotid atherosclerosis in Chinese patients with type 2 diabetes mellitus

Abstract Objective Atherosclerosis (AS) is regarded as the major cause of disability and death in diabetic patients. However, its precise pathogenesis is not entirely clear. Recent genome-wide association studies (GWAS) have revealed AS is related to some epigenetic changes. This study aimed to inve...

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Veröffentlicht in:	Thrombosis research 2015-12, Vol.136 (6), p.1149-1155
Hauptverfasser:	Shen, Jing, Zhang, Min, Sun, Mingfang, Tang, Kang, Zhou, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Asian Continental Ancestry Group - genetics Atherosclerosis Carotid Artery Diseases - etiology Carotid Artery Diseases - genetics Case-Control Studies Diabetes Mellitus, Type 2 - complications Epistasis, Genetic Female Gene-Environment Interaction Genotype Hematology, Oncology and Palliative Medicine Humans Male MicroRNAs - genetics Middle Aged miR-146a gene p300 gene Polymorphism, Single Nucleotide Single nucleotide polymorphism Type 2 diabetes mellitus
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