Targeting the NAD7 Subunit to Mitochondria Restores a Functional Complex I and a Wild Type Phenotype in the Nicotiana sylvestris CMS II Mutant Lacking nad7

The mitochondrial DNA of the Nicotiana sylvestris CMSII mutant carries a 72-kb deletion comprising the single copy nad7 gene that encodes the NAD7 subunit of the respiratory complex I (NADH-ubiquinone oxidoreductase). CMSII plants lack rotenone-sensitive complex I activity and are impaired in physio...

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Veröffentlicht in:	The Journal of biological chemistry 2005-07, Vol.280 (28), p.25994-26001
Hauptverfasser:	Pineau, Bernard, Mathieu, Chantal, Gérard-Hirne, Catherine, De Paepe, Rosine, Chétrit, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Cell Nucleus - metabolism Cloning, Molecular DNA, Complementary - metabolism DNA, Mitochondrial - metabolism Electron Transport Complex I - metabolism Electrophoresis, Polyacrylamide Gel Formate Dehydrogenases - metabolism Gene Deletion Intracellular Membranes - metabolism Mass Spectrometry Mitochondria - metabolism Mitochondrial Proteins - genetics Mitochondrial Proteins - physiology Molecular Sequence Data Mutation NAD - metabolism Nicotiana - metabolism Nicotiana sylvestris Peptides - chemistry Phenotype Plant Proteins - genetics Plant Proteins - physiology Plants, Genetically Modified Promoter Regions, Genetic Protein Binding Reverse Transcriptase Polymerase Chain Reaction RNA - metabolism Rotenone - pharmacology Solanum tuberosum - metabolism
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