Alteration of arterial smooth muscle potassium channel composition and BK sub(Ca) current modulation in hypertension

We investigated K super(+) currents and their regulation by the sarcoplasmic reticulum in mesenteric arterial smooth muscle cells of the spontaneously hypertensive rat (SHR). Using perforated patch-clamp technique, we found the overall K super(+) current density was significantly lower in adult SHR...

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Veröffentlicht in:European journal of pharmacology 2005-05, Vol.514 (2-3), p.111-119
Hauptverfasser: Zhang, Yongde, Gao, Yu-Jing, Zuo, Jianmin, Lee, Robert MKW, Janssen, Luke J
Format: Artikel
Sprache:eng
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