Evaluation of the Carcinogenic Potential of Clofibrate in the Neonatal Mouse

This study was conducted in support of the International Life Sciences Institute (ILSI) alternative carcinogenicity models initiative to evaluate the carcinogenic potential of clofibrate, a nongenotoxic peroxisome proliferator-activated receptor (PPAR) α agonist, following oral administration to neo...

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Veröffentlicht in:	International journal of toxicology 2005-09, Vol.24 (5), p.341-348
Hauptverfasser:	Nesfield, Sarah R., Williams, Thomas C., Hoivik, Debie J., Miller, Richard T., Allen, Jane S., Selinger, Krzysztof, Rickert, Douglas, Santostefano, Michael J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Carcinogenicity Tests Clofibrate - administration & dosage Clofibrate - pharmacokinetics Clofibrate - toxicity Disease Models, Animal Dose-Response Relationship, Drug Female Intubation, Gastrointestinal Male Mice Models, Animal Peroxisome Proliferators - administration & dosage Peroxisome Proliferators - pharmacokinetics Peroxisome Proliferators - toxicity Risk Assessment Time Factors
Online-Zugang:	Volltext
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