Widespread up-regulation of N-methyl- d-aspartate receptors after focal photothrombotic lesion in rat brain

Following focal brain lesions, complex adaptive processes take place in remote intact areas. The present study examines changes in NMDA ( N-methyl- d-aspartate), AMPA ((±)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) and kainate receptors following focal photothrombotic ischemic lesions usi...

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Veröffentlicht in:	Neuroscience letters 1999-10, Vol.273 (2), p.77-80
Hauptverfasser:	Que, Meishu, Schiene, Klaus, Witte, Otto W, Zilles, Karl
Format:	Artikel
Sprache:	eng
Schlagworte:	(±)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid and kainate receptors a-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - metabolism Animals Autoradiography Biological and medical sciences Brain Ischemia - etiology Brain Ischemia - metabolism Disturbed receptor balance Dizocilpine Maleate - metabolism Excitatory Amino Acid Agonists - metabolism Excitatory Amino Acid Antagonists - metabolism Focal ischemia Intracranial Thrombosis - complications Intracranial Thrombosis - etiology Kainic Acid - metabolism Light Male Medical sciences N-Methyl- d-aspartate Neurology Radiation Injuries, Experimental Rat brain Rats Rats, Wistar Receptors, AMPA - metabolism Receptors, Kainic Acid - metabolism Receptors, N-Methyl-D-Aspartate - metabolism Time Factors Up-Regulation Vascular diseases and vascular malformations of the nervous system
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