Purification of Glutathione S-Transferase pi from Erythrocytes and Evaluation of the Inhibitory Effect of Hypericin

Hypericin is a photosensitizer compound used in the photodynamic therapy (PDT). PDT is an alternative cancer treatment strategy whose function is dependent on the photosensitizers accumulating selectively in tumor cells and following visible or infra-red light induced activation lead to the apoptosi...

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Veröffentlicht in:	The Protein Journal 2015-12, Vol.34 (6), p.434-443
Hauptverfasser:	Turk, Seyhan, Kulaksiz Erkmen, Gulnihal, Dalmizrak, Ozlem, Ogus, I. Hamdi, Ozer, Nazmi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Antineoplastic Agents - pharmacology Biochemistry Bioorganic Chemistry Cancer Care and treatment Chemistry Chemistry and Materials Science Chromatography Detoxification Erythrocytes Erythrocytes - enzymology Ethylenediaminetetraacetic acid Glutathione S-Transferase pi - antagonists & inhibitors Glutathione S-Transferase pi - chemistry Glutathione S-Transferase pi - isolation & purification Glutathione transferase Histology Humans Isoenzymes Kinetics Morphology Organic Chemistry Oxidative stress Perylene - analogs & derivatives Perylene - pharmacology Photochemotherapy Proteins Regression analysis Therapy Thiols
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