Congestive heart failure is a risk factor for venous thromboembolism in bariatric surgery

Abstract Background Venous thromboembolism (VTE) is a major complication of bariatric surgery leading to significant morbidity and mortality. We sought to identify predictive factors that increase the risk of deep venous thrombosis (DVT) and pulmonary embolism (PE) using data from the National Surgi...

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Veröffentlicht in:Surgery for obesity and related diseases 2015-09, Vol.11 (5), p.1140-1145
Hauptverfasser: Haskins, Ivy N., M.D, Amdur, Richard, Ph.D, Sarani, Babak, M.D., F.A.C.S, Vaziri, Khashayar, M.D., F.A.C.S
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container_end_page 1145
container_issue 5
container_start_page 1140
container_title Surgery for obesity and related diseases
container_volume 11
creator Haskins, Ivy N., M.D
Amdur, Richard, Ph.D
Sarani, Babak, M.D., F.A.C.S
Vaziri, Khashayar, M.D., F.A.C.S
description Abstract Background Venous thromboembolism (VTE) is a major complication of bariatric surgery leading to significant morbidity and mortality. We sought to identify predictive factors that increase the risk of deep venous thrombosis (DVT) and pulmonary embolism (PE) using data from the National Surgical Quality Improvement Program (NSQIP). Methods Patients undergoing bariatric procedures from 2005–2012 were identified in the NSQIP database. Pretreatment patient characteristics were examined by laparoscopic and open treatment groups using t tests and chi-square regression. Independent associations between patient characteristics and DVT and PE were examined using logistic regression. Logistic regression was also used to examine whether patients who had postprocedure DVT or PE were more likely than those who did not have these events to have additional morbidity and mortality outcomes. Results 102,869 patients underwent bariatric surgery (96,085 laparoscopic; 6,784 open) from 2005–2012. Preoperative variables associated with increased risk of DVT in laparoscopic bariatric surgery are male gender, higher BMI, congestive heart failure (CHF), and hypertension (HTN). Preoperative variables associated with increased risk of PE in laparoscopic bariatric surgery are male gender, age greater than or equal to 60, higher BMI, African American race, chronic obstructive pulmonary disease (COPD) and CHF. There are no preoperative variables associated with an increased risk of DVT in open bariatric surgery although there is a trend toward significance with CHF. Finally, higher BMI and CHF is associated with an increased risk of PE in open bariatric surgery. Conclusions CHF is a significant risk factor for VTE in bariatric surgery. Surgeons should consider aggressive screening and VTE prophylaxis in patients with CHF and other known risk factors to decrease postoperative morbidity from VTE.
doi_str_mv 10.1016/j.soard.2014.12.020
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We sought to identify predictive factors that increase the risk of deep venous thrombosis (DVT) and pulmonary embolism (PE) using data from the National Surgical Quality Improvement Program (NSQIP). Methods Patients undergoing bariatric procedures from 2005–2012 were identified in the NSQIP database. Pretreatment patient characteristics were examined by laparoscopic and open treatment groups using t tests and chi-square regression. Independent associations between patient characteristics and DVT and PE were examined using logistic regression. Logistic regression was also used to examine whether patients who had postprocedure DVT or PE were more likely than those who did not have these events to have additional morbidity and mortality outcomes. Results 102,869 patients underwent bariatric surgery (96,085 laparoscopic; 6,784 open) from 2005–2012. Preoperative variables associated with increased risk of DVT in laparoscopic bariatric surgery are male gender, higher BMI, congestive heart failure (CHF), and hypertension (HTN). Preoperative variables associated with increased risk of PE in laparoscopic bariatric surgery are male gender, age greater than or equal to 60, higher BMI, African American race, chronic obstructive pulmonary disease (COPD) and CHF. There are no preoperative variables associated with an increased risk of DVT in open bariatric surgery although there is a trend toward significance with CHF. Finally, higher BMI and CHF is associated with an increased risk of PE in open bariatric surgery. Conclusions CHF is a significant risk factor for VTE in bariatric surgery. Surgeons should consider aggressive screening and VTE prophylaxis in patients with CHF and other known risk factors to decrease postoperative morbidity from VTE.</description><identifier>ISSN: 1550-7289</identifier><identifier>EISSN: 1878-7533</identifier><identifier>DOI: 10.1016/j.soard.2014.12.020</identifier><identifier>PMID: 25868833</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Age Factors ; Bariatric surgery ; Bariatric Surgery - adverse effects ; Bariatric Surgery - methods ; Body Mass Index ; Cohort Studies ; Confidence Intervals ; Databases, Factual ; Deep venous thrombosis ; Female ; Follow-Up Studies ; Gastroenterology and Hepatology ; Heart Failure - diagnosis ; Heart Failure - epidemiology ; Humans ; Incidence ; Laparoscopy - adverse effects ; Laparoscopy - methods ; Laparotomy - adverse effects ; Laparotomy - methods ; Logistic Models ; Male ; Middle Aged ; Morbidity ; Mortality ; NSQIP ; Obesity, Morbid - complications ; Obesity, Morbid - diagnosis ; Obesity, Morbid - surgery ; Odds Ratio ; Predictive Value of Tests ; Preoperative Care - methods ; Pulmonary embolism ; Pulmonary Embolism - epidemiology ; Pulmonary Embolism - etiology ; Pulmonary Embolism - physiopathology ; Retrospective Studies ; Risk Factors ; Sex Factors ; Surgery ; Survival Rate ; Treatment Outcome ; Venous Thromboembolism - epidemiology ; Venous Thromboembolism - etiology ; Venous Thromboembolism - physiopathology</subject><ispartof>Surgery for obesity and related diseases, 2015-09, Vol.11 (5), p.1140-1145</ispartof><rights>American Society for Bariatric Surgery</rights><rights>2015 American Society for Bariatric Surgery</rights><rights>Copyright © 2015 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c484t-c413d160e067a9be7e1d6ea944bd696bc2f7e3aeaac6bedcebcd008bb08f82783</citedby><cites>FETCH-LOGICAL-c484t-c413d160e067a9be7e1d6ea944bd696bc2f7e3aeaac6bedcebcd008bb08f82783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.soard.2014.12.020$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25868833$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Haskins, Ivy N., M.D</creatorcontrib><creatorcontrib>Amdur, Richard, Ph.D</creatorcontrib><creatorcontrib>Sarani, Babak, M.D., F.A.C.S</creatorcontrib><creatorcontrib>Vaziri, Khashayar, M.D., F.A.C.S</creatorcontrib><title>Congestive heart failure is a risk factor for venous thromboembolism in bariatric surgery</title><title>Surgery for obesity and related diseases</title><addtitle>Surg Obes Relat Dis</addtitle><description>Abstract Background Venous thromboembolism (VTE) is a major complication of bariatric surgery leading to significant morbidity and mortality. We sought to identify predictive factors that increase the risk of deep venous thrombosis (DVT) and pulmonary embolism (PE) using data from the National Surgical Quality Improvement Program (NSQIP). Methods Patients undergoing bariatric procedures from 2005–2012 were identified in the NSQIP database. Pretreatment patient characteristics were examined by laparoscopic and open treatment groups using t tests and chi-square regression. Independent associations between patient characteristics and DVT and PE were examined using logistic regression. Logistic regression was also used to examine whether patients who had postprocedure DVT or PE were more likely than those who did not have these events to have additional morbidity and mortality outcomes. Results 102,869 patients underwent bariatric surgery (96,085 laparoscopic; 6,784 open) from 2005–2012. Preoperative variables associated with increased risk of DVT in laparoscopic bariatric surgery are male gender, higher BMI, congestive heart failure (CHF), and hypertension (HTN). Preoperative variables associated with increased risk of PE in laparoscopic bariatric surgery are male gender, age greater than or equal to 60, higher BMI, African American race, chronic obstructive pulmonary disease (COPD) and CHF. There are no preoperative variables associated with an increased risk of DVT in open bariatric surgery although there is a trend toward significance with CHF. Finally, higher BMI and CHF is associated with an increased risk of PE in open bariatric surgery. Conclusions CHF is a significant risk factor for VTE in bariatric surgery. Surgeons should consider aggressive screening and VTE prophylaxis in patients with CHF and other known risk factors to decrease postoperative morbidity from VTE.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Bariatric surgery</subject><subject>Bariatric Surgery - adverse effects</subject><subject>Bariatric Surgery - methods</subject><subject>Body Mass Index</subject><subject>Cohort Studies</subject><subject>Confidence Intervals</subject><subject>Databases, Factual</subject><subject>Deep venous thrombosis</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastroenterology and Hepatology</subject><subject>Heart Failure - diagnosis</subject><subject>Heart Failure - epidemiology</subject><subject>Humans</subject><subject>Incidence</subject><subject>Laparoscopy - adverse effects</subject><subject>Laparoscopy - methods</subject><subject>Laparotomy - adverse effects</subject><subject>Laparotomy - methods</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>NSQIP</subject><subject>Obesity, Morbid - complications</subject><subject>Obesity, Morbid - diagnosis</subject><subject>Obesity, Morbid - surgery</subject><subject>Odds Ratio</subject><subject>Predictive Value of Tests</subject><subject>Preoperative Care - methods</subject><subject>Pulmonary embolism</subject><subject>Pulmonary Embolism - epidemiology</subject><subject>Pulmonary Embolism - etiology</subject><subject>Pulmonary Embolism - physiopathology</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>Surgery</subject><subject>Survival Rate</subject><subject>Treatment Outcome</subject><subject>Venous Thromboembolism - epidemiology</subject><subject>Venous Thromboembolism - etiology</subject><subject>Venous Thromboembolism - physiopathology</subject><issn>1550-7289</issn><issn>1878-7533</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1v1DAQhi0EoqXwC5CQj1w29UdiOweQ0Kp8SJU4AAdOlj8mrbdJXMbJSvvv8bKFQy8cxrZG7-uZeYaQ15w1nHF1uWtKdhgbwXjbcNEwwZ6Qc2602ehOyqf13XVso4Xpz8iLUnaMSdVp8Zycic4oY6Q8Jz-3eb6BsqQ90FtwuNDBpXFFoKlQRzGVu5oJS0Y61NjDnNdCl1vMk89QY0xlommm3mFyC6ZAy4o3gIeX5NngxgKvHu4L8uPj1fft5831109fth-uN6E17VJPLiNXDJjSrveggUcFrm9bH1WvfBCDBunAuaA8xAA-RMaM98wMRmgjL8jb07_3mH-tdRQ7pRJgHN0MtVfLdasll72QVSpP0oC5FITB3mOaHB4sZ_bI1O7sH6b2yNRyYSvT6nrzUGD1E8R_nr8Qq-DdSQB1zH0CtCUkmAPEhBAWG3P6T4H3j_xhTHMKbryDA5RdXnGuBC23pRrst-Naj1vlLWMdE638DU2HoBs</recordid><startdate>20150901</startdate><enddate>20150901</enddate><creator>Haskins, Ivy N., M.D</creator><creator>Amdur, Richard, Ph.D</creator><creator>Sarani, Babak, M.D., F.A.C.S</creator><creator>Vaziri, Khashayar, M.D., F.A.C.S</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150901</creationdate><title>Congestive heart failure is a risk factor for venous thromboembolism in bariatric surgery</title><author>Haskins, Ivy N., M.D ; Amdur, Richard, Ph.D ; Sarani, Babak, M.D., F.A.C.S ; Vaziri, Khashayar, M.D., F.A.C.S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484t-c413d160e067a9be7e1d6ea944bd696bc2f7e3aeaac6bedcebcd008bb08f82783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Bariatric surgery</topic><topic>Bariatric Surgery - adverse effects</topic><topic>Bariatric Surgery - methods</topic><topic>Body Mass Index</topic><topic>Cohort Studies</topic><topic>Confidence Intervals</topic><topic>Databases, Factual</topic><topic>Deep venous thrombosis</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gastroenterology and Hepatology</topic><topic>Heart Failure - diagnosis</topic><topic>Heart Failure - epidemiology</topic><topic>Humans</topic><topic>Incidence</topic><topic>Laparoscopy - adverse effects</topic><topic>Laparoscopy - methods</topic><topic>Laparotomy - adverse effects</topic><topic>Laparotomy - methods</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Morbidity</topic><topic>Mortality</topic><topic>NSQIP</topic><topic>Obesity, Morbid - complications</topic><topic>Obesity, Morbid - diagnosis</topic><topic>Obesity, Morbid - surgery</topic><topic>Odds Ratio</topic><topic>Predictive Value of Tests</topic><topic>Preoperative Care - methods</topic><topic>Pulmonary embolism</topic><topic>Pulmonary Embolism - epidemiology</topic><topic>Pulmonary Embolism - etiology</topic><topic>Pulmonary Embolism - physiopathology</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Sex Factors</topic><topic>Surgery</topic><topic>Survival Rate</topic><topic>Treatment Outcome</topic><topic>Venous Thromboembolism - epidemiology</topic><topic>Venous Thromboembolism - etiology</topic><topic>Venous Thromboembolism - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Haskins, Ivy N., M.D</creatorcontrib><creatorcontrib>Amdur, Richard, Ph.D</creatorcontrib><creatorcontrib>Sarani, Babak, M.D., F.A.C.S</creatorcontrib><creatorcontrib>Vaziri, Khashayar, M.D., F.A.C.S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgery for obesity and related diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Haskins, Ivy N., M.D</au><au>Amdur, Richard, Ph.D</au><au>Sarani, Babak, M.D., F.A.C.S</au><au>Vaziri, Khashayar, M.D., F.A.C.S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Congestive heart failure is a risk factor for venous thromboembolism in bariatric surgery</atitle><jtitle>Surgery for obesity and related diseases</jtitle><addtitle>Surg Obes Relat Dis</addtitle><date>2015-09-01</date><risdate>2015</risdate><volume>11</volume><issue>5</issue><spage>1140</spage><epage>1145</epage><pages>1140-1145</pages><issn>1550-7289</issn><eissn>1878-7533</eissn><abstract>Abstract Background Venous thromboembolism (VTE) is a major complication of bariatric surgery leading to significant morbidity and mortality. We sought to identify predictive factors that increase the risk of deep venous thrombosis (DVT) and pulmonary embolism (PE) using data from the National Surgical Quality Improvement Program (NSQIP). Methods Patients undergoing bariatric procedures from 2005–2012 were identified in the NSQIP database. Pretreatment patient characteristics were examined by laparoscopic and open treatment groups using t tests and chi-square regression. Independent associations between patient characteristics and DVT and PE were examined using logistic regression. Logistic regression was also used to examine whether patients who had postprocedure DVT or PE were more likely than those who did not have these events to have additional morbidity and mortality outcomes. Results 102,869 patients underwent bariatric surgery (96,085 laparoscopic; 6,784 open) from 2005–2012. Preoperative variables associated with increased risk of DVT in laparoscopic bariatric surgery are male gender, higher BMI, congestive heart failure (CHF), and hypertension (HTN). Preoperative variables associated with increased risk of PE in laparoscopic bariatric surgery are male gender, age greater than or equal to 60, higher BMI, African American race, chronic obstructive pulmonary disease (COPD) and CHF. There are no preoperative variables associated with an increased risk of DVT in open bariatric surgery although there is a trend toward significance with CHF. Finally, higher BMI and CHF is associated with an increased risk of PE in open bariatric surgery. Conclusions CHF is a significant risk factor for VTE in bariatric surgery. Surgeons should consider aggressive screening and VTE prophylaxis in patients with CHF and other known risk factors to decrease postoperative morbidity from VTE.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25868833</pmid><doi>10.1016/j.soard.2014.12.020</doi><tpages>6</tpages></addata></record>
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subjects Adult
Age Factors
Bariatric surgery
Bariatric Surgery - adverse effects
Bariatric Surgery - methods
Body Mass Index
Cohort Studies
Confidence Intervals
Databases, Factual
Deep venous thrombosis
Female
Follow-Up Studies
Gastroenterology and Hepatology
Heart Failure - diagnosis
Heart Failure - epidemiology
Humans
Incidence
Laparoscopy - adverse effects
Laparoscopy - methods
Laparotomy - adverse effects
Laparotomy - methods
Logistic Models
Male
Middle Aged
Morbidity
Mortality
NSQIP
Obesity, Morbid - complications
Obesity, Morbid - diagnosis
Obesity, Morbid - surgery
Odds Ratio
Predictive Value of Tests
Preoperative Care - methods
Pulmonary embolism
Pulmonary Embolism - epidemiology
Pulmonary Embolism - etiology
Pulmonary Embolism - physiopathology
Retrospective Studies
Risk Factors
Sex Factors
Surgery
Survival Rate
Treatment Outcome
Venous Thromboembolism - epidemiology
Venous Thromboembolism - etiology
Venous Thromboembolism - physiopathology
title Congestive heart failure is a risk factor for venous thromboembolism in bariatric surgery
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