CD40-independent Pathways of T Cell Help for Priming of CD8 super(+) Cytotoxic T Lymphocytes

In many cases, induction of CD8 super(+) CTL responses requires CD4 super(+) T cell help. Recently, it has been shown that a dominant pathway of CD4 super(+) help is via antigen-presenting cell (APC) activation through engagement of CD40 by CD40 ligand on CD4 super(+) T cells. To further study this...

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Veröffentlicht in:	The Journal of experimental medicine 2000-02, Vol.191 (3), p.541-550
Hauptverfasser:	Lu, Zhengbin, Yuan, Lingxian, Zhou, Xianzheng, Sotomayor, E, Levitsky, H I, Pardoll, D M
Format:	Artikel
Sprache:	eng
Schlagworte:	CD40 antigen CD40L protein CD8 antigen hemagglutinins influenza virus
Online-Zugang:	Volltext
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